ERIODICTIOL-7-GLUCOSIDE CAS#: 31712-49-9

ERIODICTIOL-7-GLUCOSIDE Basic information

Product Name:

ERIODICTIOL-7-GLUCOSIDE

Synonyms:

hesperetin 7-O-beta-D-glucoside
ERIODICTIOL-7-GLUCOSIDE
4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (S)-
Hesperetin 7-O-glucoside
Hesperitin-7-O-β-D-glucoside
4H-1-Benzopyran-4-one,7-(b-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-,(2S)-
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2S)-
hesperetin7-O-β-D-glucoside

CAS:

31712-49-9

MF:

C22H24O11

MW:

464.42

Mol File:

31712-49-9.mol

More

Less

ERIODICTIOL-7-GLUCOSIDE Chemical Properties

Melting point:: 206-207 °C
Boiling point:: 807.1±65.0 °C(Predicted)
Density: 1.569±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 7.16±0.40(Predicted)
color: White to off-white
InChIKey: ADSYMQORONDIDD-QENDSQSDNA-N
SMILES: O=C1C[C@@H](C2C=CC(OC)=C(O)C=2)OC2=CC(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)=CC(O)=C12 |&1:3,18,19,20,22,24,r|

More

Less

ERIODICTIOL-7-GLUCOSIDE Usage And Synthesis

Uses

Hesperetin 7-O-glucoside can be used to treat osteoporosis, scavenging free radicals, varicose veins, reducing blood lipid and decreasing blood pressure. It can also be used to promote plant growth and treat plant anti-bacterial infections.

Definition

ChEBI: A flavanone 7-O-beta-D-glucoside having hesperetin as the flavanone component.

in vivo

Hesperetin 7-O-glucoside (1 mg/kg; Oral administration; 7 days) had anti-inflammatory and protective effects in a mouse model of dextran sodium sulfate(HY-116282C) induced colitis^[2].
Hesperetin 7-O-glucoside (1-10 mg/kg; Oral gavage; 7 days) regulates intestinal flora and metabolic homeostasis in mice^[3].

Animal Model:	Dextran sodium sulfate (DSS) (HY-116282C) treated female C57BL/6N mice aged six weeks old (16-18 g)^[2]
Dosage:	1 mg/kg
Administration:	Oral administration (p.o.); 7 days
Result:	Markedly alleviated the inflammatory status in DSS-induced colitis mice, manifested by the recovered colon length from 5.91± 0.66 to 6.45 ± 0.17 cm, histopathological changes, and mRNA levels of colonic inflammatory factors including TNF-α and IL-22. Regulated the gut microbiota composition in the cecal contents and co-metabolites.

Animal Model:	Female C57BL/6N mice aged six weeks old (16-18 g)^[3]
Dosage:	1, 5 and 10 mg/kg
Administration:	Oral gavage (i.g.); 7 days
Result:	Regulated fecal microbiota and its derived metabolites, including short-chain fatty acids (SCFAs) and tryptophan metabolites (indole and its derivatives), in feces of mice. Significantly changed urinary hippurate and trimethylamine Noxide (TMAO), co-metabolites of the microbe and host. Modulated the host tricarboxylic acid cycle (TCA) involved in energy metabolism.

target

HMG-CoA Reductase | Antifection

IC 50

IL-1β; IL-22

ERIODICTIOL-7-GLUCOSIDESupplier

CHENGDU JINMAIRUI BIO-TECHNOLOGY CO.LTD Gold

Tel: 028-83133020 18280298385
Email: 1223808415@qq.com

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Email: sales@BioChemBest.com

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Email: info@chemlin.com.cn

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Email: y.liu@mail.biobiopha.com

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Email: cwb1@biopurify.cn

More

Less