JACOLINE
JACOLINE Basic information
- Product Name:
- JACOLINE
- Synonyms:
-
- JACOLINE
- Jacolin
- [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
- (20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione
- CAS:
- 480-76-2
- MF:
- C18H27NO7
- MW:
- 369.41
- Mol File:
- 480-76-2.mol
More
Less
JACOLINE Chemical Properties
- Melting point:
- 221°C
- Boiling point:
- 583.5±50.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- pka
- 12.40±0.60(Predicted)
More
Less
JACOLINE Usage And Synthesis
Description
A pyrrolizidine alkaloid which is found in Senecio Jacobea, this base has [α]20D + 48° (CHC13 ) and is hydrolyzed by alkalies to retronecine and jacolinecic acid, ClOH1S0 7. The latter contains three hydroxyl and three methyl groups.
Uses
Jacoline is a potentially carcinogenic, mutagenic, and teratogenic hepatotoxic alkaloid found in the nectar of tansy ragwort (S. jacobaea).
References
Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor., Austral. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Geissman" ibid, 12,247 (1959)
JACOLINESupplier
Wuxi Zhongkun Biochemical Technology Co., Ltd.
- Tel
- 0510-85629785 18013409632
- sales@reading-chemicals.com
Wuhan ChemFaces Biochemical Co., Ltd.
- Tel
- 18607101326 15172504745
- aileen@chemfaces.com
Biyu Biotechnology (Shanghai) Co., ltd
- Tel
- 021-26018599
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
Amadis Chemical Company Limited
- Tel
- 571-89925085
- sales@amadischem.com
More
Less