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2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene

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2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Basic information

Product Name:
2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene
Synonyms:
  • Thiophene, 2-(4-fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]-
  • 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene
  • 2-(4-Fluorophenyl)-5-(5-iodo-2-Methylbenzyl)thiophene
  • Canagliflozin iMpurity D
  • 2-((5-IODO-2-METHYLPHENYL)METHYL)-5-(4-FLUOROPHENYL)THIOPHENE
  • Canagliflozin INT5
  • Canagliflozin Intermediate1
  • 2-(4-Fluorophenyl)
CAS:
898566-17-1
MF:
C18H14FIS
MW:
408.27
EINECS:
618-312-6
Product Categories:
  • 898566-17-1
Mol File:
898566-17-1.mol
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2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Chemical Properties

Melting point:
109-110 °C
Boiling point:
450.2±45.0 °C(Predicted)
Density 
1.533
vapor pressure 
0-0Pa at 20-25℃
storage temp. 
2-8°C(protect from light)
solubility 
DMSO (Sparingly), Methanol (Slightly)
form 
Solid
color 
Pale Yellow
LogP
7.5 at pH7
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2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Usage And Synthesis

Chemical Properties

Pale Yellow Solid.

Uses

2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene is an antidiabetic agent and a Canagliflozin (C175190) intermediate. Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor and a candidate for the treatment of type 2 diabetes and obesity.

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