2-Bromo-4-(trifluoromethyl)aniline Chemical Properties

Melting point:

26-28°C

Boiling point:

109-110 °C10 mm Hg(lit.)

Density 

1,7 g/cm³

refractive index 

n20/D 1.524(lit.)

Flash point:

110 °C

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

Crystals

pka

0.70±0.10(Predicted)

color 

White

BRN 

8139978

CAS DataBase Reference

57946-63-1(CAS DataBase Reference)

NIST Chemistry Reference

Benzenamine, 2-bromo-4-(trifluoromethyl)-(57946-63-1)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36-36/37/39

RIDADR 

2810

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

6.1

HS Code 

29214990

MSDS

• Language:English Provider:4-Amino-3-bromobenzotrifluoride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Bromo-4-(trifluoromethyl)aniline Usage And Synthesis

Chemical Properties

white crystals

Uses

2-Bromo-4-(trifluoromethyl)aniline is mainly used as a raw material for organic synthesis or a reagent for chemical reactions, and can be used to prepare 2-Amino-5-trifluoromethylbenzonitrile and 2-Bromo-1-nitro-4-(trifluoromethyl) benzene among other organic heterocyclic compounds.

Synthesis

2-Bromo-4-(trifluoromethyl)aniline is prepared by reacting 4-(trifluoromethyl)aniline with N-bromosuccinimide in dichloromethane. The following is the reaction procedure:
Add 200 mL of distilled CH2Cl 2 and 4- (trifluoromethyl) aniline (20 g, 124.13 mmol) to a two neck flask. Slowly dropwise N-bromosuccinimide (24.3 g, 136.5 mmol) dissolved in CH2Cl2. When the reaction is complete, extract with CH2Cl2. Purification by column separation (EA: Hx = 1: 4) (yield: 50percent)

2-Bromo-4-(trifluoromethyl)aniline(57946-63-1)Related Product Information

• N,N-Dimethylaniline
• 3-Fluorobenzotrifluoride
• Aniline
• Glycine
• 3-Bromotoluene
• 2-Methylbenzotrifluoride
• ALTRENOGEST
• Benzotrifluoride
• 6-Aminocaproic acid
• 3-Aminobenzotrifluoride
• 2-Bromoaniline
• 1,4-Bis(trifluoromethyl)-benzene
• 2,4,5-Trifluoroaniline
• (Trifluoromethyl)trimethylsilane
• 2-Bromo-4-methylaniline
• N-Methylaniline
• Tris(hydroxymethyl)aminomethane
• 4-Bromoaniline