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2-Chloro-3-pyridylboronic acid

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2-Chloro-3-pyridylboronic acid Basic information

Product Name:
2-Chloro-3-pyridylboronic acid
Synonyms:
  • 3-Chlorpyridine-3-boronic acid
  • 2-Chloro-5-Trimethoxyphenylboronic acid
  • Boronic acid, (2-chloro-3-pyridinyl)- (9CI)
  • AKOS BRN-0504
  • 2-CHLORO-3-PYRIDINYL-BORONIC ACID
  • 2-CHLORO-3-PYRIDINEBORONIC ACID
  • 2-CHLORO-3-PYRIDYL BORONIC ACID
  • 2-CHLOROPYRIDINE-3-BORONIC ACID
CAS:
381248-04-0
MF:
C5H5BClNO2
MW:
157.36
EINECS:
624-435-6
Product Categories:
  • Boronic Acids
  • Boronic Acids and Derivatives
  • blocks
  • BoronicAcids
  • Heteroaryl
  • Boric acid series
  • Pyridines
  • Pyridine
  • Boronic Acids & Esters
  • Boronic acid
  • Organoborons
  • Boronic Acids & Esters
  • pyridine series
  • Boronate Ester
  • BORONICACID
  • Potassium Trifluoroborate
Mol File:
381248-04-0.mol
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2-Chloro-3-pyridylboronic acid Chemical Properties

Melting point:
121-134 °C
Boiling point:
349.3±52.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
soluble in Methanol
form 
Crystalline Powder
pka
6.59±0.58(Predicted)
color 
White
BRN 
9119913
InChIKey
VRDAOVQZVXYRNH-UHFFFAOYSA-N
CAS DataBase Reference
381248-04-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-36-36/37/39-24/25-22
RIDADR 
2811
WGK Germany 
3
Hazard Note 
Irritant/Keep Cold
HazardClass 
IRRITANT
HS Code 
29333990

MSDS

  • Language:English Provider:ALFA
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2-Chloro-3-pyridylboronic acid Usage And Synthesis

Chemical Properties

White solid

Uses

Reactant for:

  • Synthesis of Et canthinone-3-carboxylates from Et 4-bromo-6-methoxy-1,5-naphthyridine-3-carboxylate via a Pd-catalyzed Suzuki-Miyaura coupling and a Cu-catalyzed amidation reaction
  • Preparation of arylmethylpyrrolidinylmethanols and amine derivatives via reaction with MIDA followed by Suzuki reaction with halides or amination with amines
  • Preparation of arylazabicyclooctane derivatives as potential arginine vasopressin receptor antagonists
  • Regioselective preparation of halo-oligopyridines and oligopyridines by the Suzuki-Miyaura cross-coupling reaction

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