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2,4-Bis(trifluoromethyl)phenylboronic acid

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2,4-Bis(trifluoromethyl)phenylboronic acid Basic information

Product Name:
2,4-Bis(trifluoromethyl)phenylboronic acid
Synonyms:
  • 2,4-BIS(TRIFLUOROMETHYL)PHENYLBORONIC A&
  • 2,4-Bis(Trifluoromethyl)Phenyl
  • 2,4-Bis(trifluoromethyl)benzeneboronic acid 98%
  • 2,4-Bis(trifluoromethyl)benzeneboronicacid98%
  • 2,4-BIS(TRIFLUOROMETHYL)PHENYLBORONIC ACID
  • 2,4-BIS(TRIFLUOROMETHYL)BENZENEBORONIC ACID
  • AKOS BRN-0143
  • 2,4-Bis(trifluoromethyl)phenylboronic Acid (contains varying amounts of Anhydride)
CAS:
153254-09-2
MF:
C8H5BF6O2
MW:
257.93
EINECS:
604-892-8
Product Categories:
  • blocks
  • BoronicAcids
  • Substituted Boronic Acids
  • Boronic Acids & Esters
  • Phenyls & Phenyl-Het
  • Aryl
  • Halogenated
  • Organoborons
  • B (Classes of Boron Compounds)
  • Boronic Acids
  • Boronic acid
  • Boronic Acids & Esters
  • Boronic Acids
  • Boronic Acids and Derivatives
  • Phenyls & Phenyl-Het
Mol File:
153254-09-2.mol
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2,4-Bis(trifluoromethyl)phenylboronic acid Chemical Properties

Melting point:
148-150
Boiling point:
245.4±50.0 °C(Predicted)
Density 
1.50±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
7.40±0.58(Predicted)
color 
White to Light yellow
CAS DataBase Reference
153254-09-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C,Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-24/25
WGK Germany 
3
Hazard Note 
Corrosive
HazardClass 
IRRITANT
HS Code 
29319090

MSDS

  • Language:English Provider:ALFA
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2,4-Bis(trifluoromethyl)phenylboronic acid Usage And Synthesis

Chemical Properties

White crystalline

Uses

Reactant for preparation of:

  • Pyrrolo[2,3-d]pyrimidin-4-ones as corticotropin-releasing factor 1 receptor antagonists with a carbonyl-based hydrogen bonding acceptor
  • Biaryl pyrazole carboxamides as sodium channel blockers for treatment of neuropathic pain
  • Biphenylketones as dual modulators of inflammation and bone loss
  • (Biphenylyl)pyrazolecarboxamides and their voltage-gated sodium channel Nav1.7 blocking structure-activity relationship
  • N-hydroxyalkyl biphenylsulfonamides as inhibitors of bone resorption
  • 1,3,6,8a-tetraazaacenaphthylene derivatives and study of their activity as corticotropin-releasing factor-1 antagonists
  • Blue luminescent iridium phenylpyridine complexes

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