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SARPAGINE

Basic information Safety Supplier Related

SARPAGINE Basic information

Product Name:
SARPAGINE
Synonyms:
  • SARPAGINE
  • sarpagan-10,17-diol
  • Raupine
  • Sarpagane-10,17-diol
  • Raupin
CAS:
482-68-8
MF:
C19H22N2O2
MW:
310.39
EINECS:
207-583-2
Product Categories:
  • Alkaloids
Mol File:
482-68-8.mol
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SARPAGINE Chemical Properties

Melting point:
320°C
Boiling point:
450.55°C (rough estimate)
alpha 
D20 +54° (c = 0.5 in pyridine)
Density 
1.1396 (rough estimate)
refractive index 
1.5600 (estimate)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
10.24±0.40(Predicted)
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Safety Information

RIDADR 
1544
HazardClass 
6.1(b)
PackingGroup 
III
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SARPAGINE Usage And Synthesis

Description

This base has been isolated from Rauwolfia serpentina and is an isomer of Ajmalinine (q.v.). Pharmacologically it has between three and four times the effect of the total Rauwolfia alkaloids on isolated rabbit uterus and is very specific. In the cat, the blood pres~ure is lowered by 0.5-2.0 mgm per kilo body weight. The toxicity is low.

Definition

ChEBI: An indole alkaloid that is sarpagan bearing hydroxy groups at positions 10 and 17.

References

Bodendorf, Eder., Naturwis<., 40, 342 (1953)

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