ChemicalBook > Product Catalog > Organic Chemistry > Alcohols,Phenols,Phenol alcohols > 2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL
2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL
2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL Basic information
- Product Name:
- 2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL
- Synonyms:
-
- 2-(4-tert-butylphenoxy)-1-cyclohexanol
- 2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL
- 2-(p-t-butylphenoxy)cyclohexanol
- 2-(p-tert-butylphenoxy)-cyclohexano
- CYCLOHEXANOL-2-(4-TERT-BUTYL-PHENOXY)
- 2-(4-tert-butylphenoxy)cyclohexan-1-ol
- 2-[4-(1,1-DIMETHYLETHYL)PHENOXY]CYCLOHEXANOL
- propargite metab.
- CAS:
- 1942-71-8
- MF:
- C16H24O2
- MW:
- 248.36
- EINECS:
- 217-732-3
- Mol File:
- 1942-71-8.mol
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2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL Chemical Properties
- Melting point:
- 93-95 °C
- Boiling point:
- 365.7±42.0 °C(Predicted)
- Density
- 1.036±0.06 g/cm3(Predicted)
- storage temp.
- Store at 4℃
- solubility
- 24.84mg/ml in DMSO, 24.84mg/ml in Ethanol
- form
- powder
- pka
- 14.60±0.40(Predicted)
- color
- white to beige
- EPA Substance Registry System
- 2-(p-tert-Butylphenoxy)cyclohexanol (1942-71-8)
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Safety Information
- Hazardous Substances Data
- 1942-71-8(Hazardous Substances Data)
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2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL Usage And Synthesis
Biological Activity
tBPC is a postitive allosteric modulator of the neuropeptide Y (NPY) Y4 receptor, which is predominantly expressed in the gastrointestinal tract and activated most strongly by pancreatic polypeptide (PP). tBPC was shown to potentiate Y4R activity in G-Protein signaling and arrestin3 recruitment and to potentiate the native PP response. tBPC was selective for Y4R over other Neuropeptide Y receptors and showed no effect on the efficacy (Emax) or potency (EC50) of the NPY signal response at the Y1, Y2, or Y5 receptors at 30 μM.
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