BUSULFAN-D8 Chemical Properties

Melting point:

112-1140C

storage temp. 

-20°C Freezer

solubility 

DMF: 16.7 mg/ml,DMSO: 16.7 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml

form 

A crystalline solid

color 

White to off-white

BUSULFAN-D8 Usage And Synthesis

Description

Busulfan-d₈ is intended for use as an internal standard for the quantification of busulfan by GC- or LC-MS. Busulfan is an alkyl sulfonate that acts as an alkylating antineoplastic agent. It forms both intra- and interstrand crosslinks on DNA. In mammals, busulfan causes profound and prolonged reduction in the generation of hematopoietic progenitors without significantly affecting lymphocyte levels or humoral antibody responses.

Chemical Properties

White Solid

Uses

Alkylating agent with antileukemic activity. Antineoplastic

BUSULFAN-D8(116653-28-2)Related Product Information

• Busulfan
• Busulfan IMpurity 1
• 1-Acetate 4-Methanesulfonate 1,4-Butanediol
• Busulfan IMpurity 2
• 1,4-Butanediol, MonoMethanesulfonate
• acetyl Methanesulfonate
• 1,4-BUTANEDIOL-2,2,3,3-D4
• BUSULFAN-D8
• 1,4-BUTANEDIOL-1,1,2,2,3,3,4,4-D8
• 1,4-BUTANE-1,1,4,4-D4-DIOL