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Imatinib (Piperidine)-N-oxide

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Imatinib (Piperidine)-N-oxide Basic information

Product Name:
Imatinib (Piperidine)-N-oxide
Synonyms:
  • 4-oxide iMatinib
  • IMatinib (Piperidine)-4-oxide
  • 4-[(4-Methyl-4-oxido-piperazin-4-iuM-1-yl)Methyl]-N-[4-Methyl-3-[[4-(3-pyridyl)pyriMidin-2-yl]aMino]phenyl]benzaMide
  • Imatinib Impurity D
  • Imatinib (Piperidine)-N1-Oxide
  • iMatinib related substance D
  • Imatinib-piperidine-4-N-oxide (under development)
  • 4-[(4-Methyl-4-oxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide
CAS:
571186-91-9
MF:
C29H31N7O2
MW:
509.6
Product Categories:
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Impurities
Mol File:
571186-91-9.mol
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Imatinib (Piperidine)-N-oxide Chemical Properties

Melting point:
146-149°C
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly, Heated)
pka
13.23±0.70(Predicted)
form 
Solid
color 
Pale Yellow to Yellow
Stability:
Hygroscopic
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Safety Information

HS Code 
29333990
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Imatinib (Piperidine)-N-oxide Usage And Synthesis

Chemical Properties

Pale Yellow Solid

Uses

Imatinib (Piperidine)-4-oxide (Imatinib EP Impurity J) is an impurity of Imatinib (Gleevec) (G407000). Imatinib impurity D. It is a COVID19-related research product.

Uses

A metabolite of Imatinib

Uses

Imatinib (Piperidine)-4-oxide is an impurity of Imatinib (Gleevec) (G407000). Imatinib impurity D.

Definition

ChEBI: CGP71422 is a member of benzamides.

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