Pentafluorobenzoyl chloride Chemical Properties

Boiling point:

158-159 °C(lit.)

Density 

1.601 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.453(lit.)

Flash point:

None

storage temp. 

Store below +30°C.

solubility 

soluble in Chloroform

form 

Liquid

Specific Gravity

1.601

color 

Clear colorless to light yellow

Water Solubility 

decomposes

Sensitive 

Lachrymatory

BRN 

2054397

Stability:

Moisture Sensitive

InChIKey

MYHOHFDYWMPGJY-UHFFFAOYSA-N

CAS DataBase Reference

2251-50-5(CAS DataBase Reference)

NIST Chemistry Reference

Pentafluorobenzoyl chloride(2251-50-5)

Safety Information

Hazard Codes 

C

Risk Statements 

14-34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

F 

10-19-21

Hazard Note 

Corrosive/Lachrymator

HazardClass 

8

PackingGroup 

II

HS Code 

29163900

MSDS

• Language:English Provider:2,3,4,5,6-Pentafluorobenzoyl chloride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Pentafluorobenzoyl chloride Usage And Synthesis

Description

Pentafluorobenzoyl chloride is the acid chloride of pentafluorobenzoic acid. It is a sensitive derivatising reagent for the analysis of amines, amides and phenols by electron capture gas chromatography. It has a role as a chromatographic reagent. It is an acyl chloride and a perfluorinated compound. It derives from a pentafluorobenzoic acid.
2,3,4,5,6-Pentafluorobenzoyl chloride was used for derivatization of 5-androstenediol, testosterone, estradiol , dihydrotestosterone and estrone in a study to determine their serum levels. 2,3,4,5,6-Pentafluorobenzoyl chloride was used to derivatize dimethylamine(DMA) in study to develop a rapid and accurate GC–MS method for determination of DMA in human urine. 2,3,4,5,6-Pentafluorobenzoyl chloride was used in a study to detect the presence of Enterobacter cloacae in cultures of Leuconostoc mesenteroide by gas chromatography/mass spectrometry.

Chemical Properties

clear colorless to light yellow liquid

Uses

Pentafluorobenzoyl Chloride is a useful analytical reagent in the derivatization amphetamines as well as other primary amines.

Uses

A reagent used for deriving primary amines. 2,3,4,5,6-Pentafluorobenzoyl chloride was used for derivatization of 5-androstenediol, testosterone, estradiol , dihydrotestosterone and estrone in a study to determine their serum levels. 2,3,4,5,6-Pentafluorobenzoyl chloride was used to derivative dimethylamine(DMA) in study to develop a rapid and accurate GC-MS method for determination of DMA in human urine. It was used in a study to detect the presence of Enterobacter cloacae in cultures of Leuconostoc mesenteroide by gas chromatography/mass spectrometry.

Uses

Pentafluorobenzoyl chloride can be used for the derivatization of a variety of analytes including biological amines. There is an extensive use for the derivatization of lipids.

Definition

ChEBI: The acid chloride of pentafluorobenzoic acid. It is a sensitive derivatising reagent for the analysis of amines, amides and phenols by electron capture gas chromatography.

Pentafluorobenzoyl chloride(2251-50-5)Related Product Information

• Oxalyl chloride
• Penfluridol
• Sodium chloride
• Zinc chloride
• Ammonium chloride
• 2,3,4,5-Tetrafluorobenzoyl chloride
• 3-Methylbenzoyl chloride
• 4-Fluorobenzoyl chloride
• 2-Fluorobenzoyl chloride
• Thionyl chloride
• Benzoyl chloride
• p-Toluoyl chloride
• Potassium chloride
• Choline chloride
• Calcium chloride
• Pentafluorobenzene
• Pentafluorobenzoic acid
• PENTAFLUORONITROBENZENE