2-Butynoic acid Chemical Properties

Melting point:

78-80 °C (lit.)

Boiling point:

200-203°C

Density 

0,9641 g/cm³

refractive index 

1.3918 (estimate)

Flash point:

200-203°C

storage temp. 

Sealed in dry,2-8°C

solubility 

water: soluble50mg/mL, clear to very slightly hazy, colorless to very faintly yellow

form 

Powder

pka

2.62(at 25℃)

color 

White to yellow

Water Solubility 

Soluble in water. Slightly soluble in methanol and chloroform.

BRN 

1740205

InChIKey

LUEHNHVFDCZTGL-UHFFFAOYSA-N

CAS DataBase Reference

590-93-2(CAS DataBase Reference)

NIST Chemistry Reference

2-Butynoic acid(590-93-2)

EPA Substance Registry System

2-Butynoic acid (590-93-2)

Safety Information

Hazard Codes 

C

Risk Statements 

34-20/21/22

Safety Statements 

26-27-36/37/39-45

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29161900

MSDS

• Language:English Provider:2-Butynoic acid
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2-Butynoic acid Usage And Synthesis

Chemical Properties

white to yellow powder

Uses

Synthon employed in a variety of reactions, including cycloacylation of phenols to flavones and chromones,1 and cyclization to γ-butyrolactones.2

Uses

2-Butynoic acid is used as an intermediate in organic synthesis and pharmaceuticals. It is used as a synthon in various reactions, which includes cylcoalkylation of phenols to flavones and chromones. It is involved in the cyclization of gamma-butyrolactones. It is also used in the synthesis of Z-trisubstituted olefins through μ-alkylation. It plays an important role in the preparation of chirally pure 1,2,3,4-tetrahydroisoquinoline analogs, which finds application as anti-cancer agents.

General Description

The rotational spectrum of 2-butynoic acid was measured by pulsed supersonic-jet Fourier transform microwave spectroscopy.

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