Tetrahydroberberine Chemical Properties

Melting point:

166.5 °C

Boiling point:

476.1±45.0 °C(Predicted)

Density 

1.33±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO: >10 mg/mL, soluble

form 

solid

pka

6.53±0.20(Predicted)

color 

yellow

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

Safety Statements 

36

WGK Germany 

3

Toxicity

LD50 in mice (mg/kg): 940 orally; 790 s.c.; 100 i.v. (Sadritdinov, Sultanov)

MSDS

• Language:English Provider:SigmaAldrich

Tetrahydroberberine Usage And Synthesis

Uses

Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.

Uses

Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberberine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.

Definition

ChEBI: A berberine alkaloid that is 5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline substituted by methoxy groups at positions 9 and 10.

Tetrahydroberberine(522-97-4)Related Product Information

• (-)-Huperzine A
• Leflunomide
• Formoterol fumarate dihydrate
• Artemisinin
• Andrographolide
• Berbamine hydrochloride
• BERBERINE CHLORIDE
• Rotundine
• epiberberine
• Coptisine chloride
• Berberine hydrochloride
• TETRAHYDROBERBERINE(CANADINE)(P),TETRAHYDROBERBERINE(CANADINE)(P)
• 7-(4-chlorobenzyl)-7,8,13,13a-tetrahydroberberine
• DL-TETRAHYDROBERBERINE,TETRAHYDROBERBERINE,CANADINE,DL-CANADINE
• .Alpha.-Canadine methochloride
• 1-tetrahydroberberine-camphor sulfonate
• canadine hydrochloride
• (D,L)-TETRAHYDROBERBERINE(CANADINE),(D,L)-TETRAHYDROBERBERINE(CANADINE)