H-GLU-TRP-OH Chemical Properties

Melting point:

121-122℃

Boiling point:

738.9±60.0 °C(Predicted)

Density 

1.428

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

solubility 

DMSO : 15.5 mg/mL (46.50 mM)

pka

3.09±0.10(Predicted)

H-GLU-TRP-OH Usage And Synthesis

Uses

Treatment of Kaposi’s sarcoma and solid tumor cancers (angiogenesis inhibitor); immunomodulator.

Uses

H-Glu-Trp-OH, has show to have potential antiangiogenic and immunomodulating activities. It inhibits vascular endothelial growth factor (VEGF), which may inhibit angiogenesis. This agent has also been reported to stimulate the immune response to hepatitic C virus and intracellular bacterial infections.

Definition

ChEBI: A dipeptide composed of L-glutamic acid and L-tryptophan joined by a peptide linkage.

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