D(-)-Glutamic acid
D(-)-Glutamic acid Basic information
- Product Name:
- D(-)-Glutamic acid
- Synonyms:
-
- (2R)-2-Aminoglutaric acid
- D-α-AMinoglutaric acid
- D-1-AMinopropane-1,3-dicarboxylic acid
- D(-)-GlutaMic acid, 99+% 25GR
- D(-)-GlutaMic acid, 99+% 5GR
- (2R)-GlutaMic Acid
- NSC 77686
- D-Glutaminic acid
- CAS:
- 6893-26-1
- MF:
- C5H9NO4
- MW:
- 147.13
- EINECS:
- 230-000-8
- Product Categories:
-
- amino acid
- Glutamate receptor
- Amino ACIDS SERIES
- Glutamic acid [Glu, E]
- Amino Acids and Derivatives
- alpha-Amino Acids
- Amino Acids
- Biochemistry
- for Resolution of Bases
- Optical Resolution
- Synthetic Organic Chemistry
- Nutritional Supplements
- Amino Acids
- Mol File:
- 6893-26-1.mol
D(-)-Glutamic acid Chemical Properties
- Melting point:
- 200-202 °C (subl.)(lit.)
- alpha
- -31.3 º (c=10, 2 N HCl)
- Boiling point:
- 267.21°C (rough estimate)
- Density
- 1.5380
- refractive index
- 1.4210 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Water (Slightly)
- form
- Powder
- pka
- pK1:2.162(＋1);pK2:4.272(0);pK3:9.358(－1) (25°C)
- color
- White to off-white
- Water Solubility
- 7 g/L (20 ºC)
- Merck
- 14,4469
- BRN
- 1723800
- InChIKey
- WHUUTDBJXJRKMK-GSVOUGTGSA-N
- LogP
- -0.969 (est)
- CAS DataBase Reference
- 6893-26-1(CAS DataBase Reference)
- NIST Chemistry Reference
- D-Glutamic acid(6893-26-1)
- EPA Substance Registry System
- D-Glutamic acid (6893-26-1)
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 3
- F
- 10
- TSCA
- Yes
- HS Code
- 29224200
MSDS
- Language:English Provider:D-2-Aminoglutaric acid
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
D(-)-Glutamic acid Usage And Synthesis
Chemical Properties
White cryst. powder
Uses
D-Glutamic Acid is the unnatural (R)-enantiomer of Glutamic Acid, a non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. Glutamic Acid is also a key molecule in cellular metabolism.
Uses
D-Glutamic acid acts as a superior to alpha ketoglutarate. It helps in the growth of Lactobacillus arabinosus. It can inhibit the IgE binding to peanut allergens. It is widely used in pharmaceuticals and foods.
Uses
D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors.
Definition
ChEBI: An optically active form of glutamic acid having D-configuration.
General Description
D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.
Biological Activity
Excitatory amino acid acting at NMDA receptors; less active than the L-isomer.
Biochem/physiol Actions
Unnatural isomer of glutamic acid.
storage
Room temperature
D(-)-Glutamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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D(-)-Glutamic acid(6893-26-1)Related Product Information
- Polyglutamic acid
- L-Glutamic acid
- L-Pyroglutamic acid
- Citric acid
- Glycine
- Ethyl 2-(Chlorosulfonyl)acetate
- GLDH
- D-Serine
- D(+)-Tryptophan
- D-Valine
- D-Cystine
- D-Prolinamide
- D-Glutamic Acid diethyl ester hydrochloride
- Glutamic acid
- Ascoric Acid
- Boc-D-Glu-OBzl
- Folic acid
- L-Glutamic acid dibenzyl ester 4-toluenesulfonate