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2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol

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2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol Basic information

Product Name:
2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol
Synonyms:
  • octylphenoleo(20)
  • octylphenoleo(3)
  • octylphenoxypoly(ethyleneoxy)ethanol
  • op1062
  • ope-3
  • poly(ethyleneoxide)octylphenylether
  • polyethyleneglycolmono(octyl)phenylether
  • polyethyleneglycolmono(octylphenyl)ether
CAS:
9036-19-5
MF:
C18H30O3
MW:
294.43
EINECS:
999-999-2
Product Categories:
  • Core Bioreagents
  • Detergents A to ZDetergents
  • DetergentsDetergents
  • Non-Ionic
  • Research Essentials
Mol File:
9036-19-5.mol
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2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol Chemical Properties

Melting point:
0.05°C
Boiling point:
586.77°C (rough estimate)
Density 
1.06 g/mL at 20 °C
vapor pressure 
<0.01 hPa (20 °C)
refractive index 
n20/D 1.492
Flash point:
>230 °F
storage temp. 
Store at +5°C to +30°C.
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Liquid
color 
Yellow
PH
5.0-8.0 (10g/l, H2O, 20℃)
Water Solubility 
Miscible with water.
Merck 
13,6793
BRN 
2315025
Dielectric constant
9.8(29.0℃)
CAS DataBase Reference
9036-19-5(CAS DataBase Reference)
EPA Substance Registry System
Polyethylene glycol mono(1,1,3,3-tetramethylbutyl)phenyl ether (9036-19-5)
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Safety Information

Hazard Codes 
Xn,Xi,N
Risk Statements 
41-38-22-51/53-52/53
Safety Statements 
26-39-61
RIDADR 
UN 3082 9 / PGIII
WGK Germany 
2
RTECS 
MD0907600
3-8-10-23
TSCA 
Yes
HS Code 
34021300
Hazardous Substances Data
9036-19-5(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 1900 - 5000 mg/kg LD50 dermal Rabbit > 3000 mg/kg
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2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol Usage And Synthesis

Uses

Triton? X-100 has been used:

  • In immunohistochemistry for staining the Flat-mount retinas
  • Along with ice-cold PBS (phosphate buffered saline) in suspension of cells for cell DNA analysis and Annexin V assay
  • To permeabilise cells during Immunofluorescent microscopic studies
  • As a positive control in LDH assay to determine the cell membrane integrity
  • For estimating the lipase activity in postheparin plasma by using modified Belfrage and Vaughan radioenzymatic procedure
  • For the preparation of outer membrane protein exctract
  • As a component of extraction buffer along with tris-HCl, NaCl, CaCl2, ZnCl2, Brij 35 for homogenization of mice lung cells
  • In the treatment of tissue sections for Immunofluorescence labeling

Uses

0·3% Triton? X-100 in TBS has been used for permeabilization of retinas before immunostaining. 0.5% Triton X-100 has been used for astrocyte cell lysis.

Uses

Triton?-X has been used:

  • In the permeabilization of cells for immunofluorescence staining
  • As a component of lysis buffer in western blot analysis
  • As a component of Tris-buffered saline for the preparation of cell sections in Immunogold labelling for electron microscope

General Description

Octophenolpoly(ethyleneglycolether)n
Especially used for purification in membrane research
Triton X-100 is a water soluble, non-ionic surfactant. It exhibits a strong hydrogen bonding with water molecule in temperature dependent manner. It has a wide application area such as in isolation and solubilization of protein, DNA extraction and emulsification.

Biochem/physiol Actions

Widely used non-ionic surfactant for recovery of membrane components under mild non-denaturing conditions.

Safety Profile

Moderately toxic by ingestion.When heated to decomposition it emits acrid smoke andirritating fumes.

Safety Profile

Moderately toxic by ingestion. Aneye irritant. When heated to decomposition it emits acridsmoke and irritating fumes.

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