ChemicalBook > Product Catalog > API > Antineoplastic agents > Other antineoplastic Drugs > 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt
2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt
2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt Basic information
- Product Name:
- 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt
- Synonyms:
-
- Lobaplatin
- 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt
- Lobaplatin Impurity 1
- 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt USP/EP/BP
- 2-(aminomethyl)cyclobutyl]methanamine,2-hydroxypropanoicacid,platinum
- CAS:
- 131374-93-1
- MF:
- C9H18N2O3Pt+2
- MW:
- 397.32882
- Mol File:
- 131374-93-1.mol
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2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt Usage And Synthesis
Chemical Properties
Lobaplatin (D-19466), is a third-generation platinum-based antitumor drug developed by German ASTA Medica AG after cisplatin and carboplatin.
Indications
Lobaplatin is mainly used in the treatment of advanced breast cancer, small cell lung cancer and chronic myeloid leukemia.
Side effects
Lobaplatin has a clear cytotoxic effect on a variety of animal and human tumor cell lines, which is equivalent to or better than the tumor suppressor effect of cisplatin, and overcomes the nephrotoxicity and digestive tract toxicity of cisplatin.
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