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2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt

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2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt Basic information

Product Name:
2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt
Synonyms:
  • Lobaplatin
  • 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt
  • Lobaplatin Impurity 1
  • 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt USP/EP/BP
  • 2-(aminomethyl)cyclobutyl]methanamine,2-hydroxypropanoicacid,platinum
CAS:
131374-93-1
MF:
C9H18N2O3Pt+2
MW:
397.32882
Mol File:
131374-93-1.mol
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2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt Usage And Synthesis

Chemical Properties

Lobaplatin (D-19466), is a third-generation platinum-based antitumor drug developed by German ASTA Medica AG after cisplatin and carboplatin.

Indications

Lobaplatin is mainly used in the treatment of advanced breast cancer, small cell lung cancer and chronic myeloid leukemia.

Side effects

Lobaplatin has a clear cytotoxic effect on a variety of animal and human tumor cell lines, which is equivalent to or better than the tumor suppressor effect of cisplatin, and overcomes the nephrotoxicity and digestive tract toxicity of cisplatin.

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