Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Chemical Properties

Boiling point:

100.1℃ at 101.325kPa

Density 

d20 1.19

vapor pressure 

0.003-17Pa at 20-45℃

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Soluble), DMSO (Slightly), Methanol (Slightly), Water

form 

Liquid

PH

3.43 at 20℃ and 10g/L

LogP

-0.34-0.81 at 10-30℃ and pH5-9

Surface tension

72.6-73mN/m at 1-1.106g/L and 19.5-20℃

Dissociation constant

2.81-4.2 at 20-25℃

EPA Substance Registry System

5-Chloro-2-methyl-3(2H)-isothiazolone mixt. with 2-methyl-3(2H)-isothiazolone (55965-84-9)

Safety Information

Toxicity

LD50 (mg/kg) orally in rabbits: 30; i.p. in male, female rats: 4.6, 4.3; LC50 (6 day) in trout, sunfish (mg/l): 0.14, 0.54; LC50 (8 day dietary) in Bobwhite quail, Peking duck (mg/kg/day): >60, >100 (J. Am. Coll. Toxicol.)

Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Usage And Synthesis

Description

Kathon 886 metalwork fluid is a mixture of the two isothiazoliones contained in Kathon CG, at a 13.9% concentration. It is mainly contained in metalwork fluids. As an active component of Aigezid Ⅱ and contained in a water bath used for phtotographic development, it caused contact dermatitis in a photograph developer.

Description

Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) is a mixture of isothiazolinone-derived biocides. It is effective against Gram-positive and Gram-negative bacteria with MIC values of 0.0002, 0.0002, 0.00005, and 0.00005% (w/w) for S. aureus, P. aeruginosa, A. niger, and C. albicans, respectively. MCIT/MIT can elicit contact sensitization. Formulations containing MCIT/MIT have been used for controlling microbial growth in industrial and household products.

Uses

Antimicrobial preservative in cosmetics, hygeine products, paints, emulsions, cutting oils, paper coatings, and water storage and cooling units.

Hazard

A poison by ingestion.

Contact allergens

Kathon? CG (CG = cosmetic grade) is a 3:1 mixture of CMI and MI, at a 1.5% concentration. It is used for cosmetics and toiletries, metalworking fluids or paints, in which it can be added only periodically or in color film developers. Kathon? 886 MW (MW = metalworking fluids) is a mixture CMI/MI mixture at a 13.9% concentration, mainly contained in metalworking fluids. Kathon? FP 1.5 contains MCI/MI at 1.5% concentration in propylene glycol. Kathon? LX (LX = LateX) contains MCI/MI at a tenfold concentration of Kathon? CG. Kathon? WT (WT = water treatment) is a MCI/MI mixture used in the paper industry. Parmetol? K40, Parmethol? DF 12 and Parmetol? DF 35, Parmetol? A 23, Parmetol? K50, and Parmetol? DF 18 are other brand names of MCI/MI.

Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT)(55965-84-9)Related Product Information

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