ChemicalBook > Product Catalog > API > Blood System Drugs > Anticoagulant and Antiplatelet Drugs > Ozagrel sodium
Ozagrel sodium
Ozagrel sodium Basic information
- Product Name:
- Ozagrel sodium
- Synonyms:
-
- OZAGREL SODIUM
- (E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]acrylic acid sodium salt
- Athrombone
- D01684
- Ozagrel sodium (jan)
- Ozapen
- Ozapen (tn)
- sodium (E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)acrylate
- CAS:
- 189224-26-8
- MF:
- C13H11N2NaO2
- MW:
- 250.23
- EINECS:
- 1806241-263-5
- Mol File:
- 189224-26-8.mol
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Ozagrel sodium Chemical Properties
- storage temp.
- Store at -20°C
- form
- Solid
- color
- White to off-white
- Water Solubility
- Water: ≥ 44 mg/mL (175.84 mM)
- InChI
- InChI=1S/C13H12N2O2.Na/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15;/h1-8,10H,9H2,(H,16,17);/q;+1/p-1/b6-5+;
- InChIKey
- NCNYJCOBUTXCBR-IPZCTEOASA-M
- SMILES
- [Na+].C([O-])(=O)/C=C/C1=CC=C(CN2C=NC=C2)C=C1
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Ozagrel sodium Usage And Synthesis
Chemical Properties
White powder
Uses
Ozagrel sodium (OKY-046 sodium) is a thromboxane A2 (TXA2) synthase inhibitor. Ozagrel sodium is an antiplatelet agent, which selectively inhibits human platelet aggregation with an IC50 of 53.12 μM[1].
IC 50
TXA2
References
[1] Max Seidy Saito, et al. Antiplatelet pyrazolopyridines derivatives: pharmacological, biochemical and toxicological characterization. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1591-601. DOI:10.3109/14756366.2016.1158712
Ozagrel sodiumSupplier
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