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(-)-3-Demethylcolchicine

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(-)-3-Demethylcolchicine Basic information

Product Name:
(-)-3-Demethylcolchicine
Synonyms:
  • (-)-3-Demethylcolchicine
  • (S)-7-Acetylamino-6,7-dihydro-3-hydroxy-1,2,10-trimethoxybenzo[a]heptalen-9(5H)-one
  • 3-Demethylcolchicine
  • 3-O-Demethylcolchicine
  • 3-DesMethylcolchicine
  • N-[(7S)-5,6,7,9-Tetrahydro-3-hydroxy-1,2,10-triMethoxy-9-oxobenzo[a]heptalen-7-yl]-acetaMide
  • N-[[(7S)-3-Hydroxy-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalene]-7α-yl]acetamide
  • O3-Demethylcolchicine
CAS:
7336-33-6
MF:
C21H23NO6
MW:
385.41
Product Categories:
  • Chiral Reagents
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
7336-33-6.mol
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(-)-3-Demethylcolchicine Chemical Properties

Melting point:
163-166°C
Boiling point:
768.3±60.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO : 100 mg/mL (259.46 mM; Need ultrasonic)
form 
A solid
pka
9.53±0.40(Predicted)
color 
White to yellow
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Safety Information

Toxicity
LD50 intraperitoneal in mouse: 570ug/kg
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(-)-3-Demethylcolchicine Usage And Synthesis

Chemical Properties

Yellow Solid

Uses

A metabolite of Colchicine (C640000). Has shown anti-tumor activity.

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(-)-3-Demethylcolchicine(7336-33-6)Related Product Information