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3-Hydroxy-6-methylpyridine

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3-Hydroxy-6-methylpyridine Basic information

Product Name:
3-Hydroxy-6-methylpyridine
Synonyms:
  • 6-methyl-3-pyridino
  • 2-METHYL-5-HYDROXY PYRIDINE
  • 5-HYDROXY-2-PICOLINE
  • 5-HYDROXY-2-METHYLPYRIDINE
  • 6-METHYLPYRIDIN-3-OL
  • 6-METHYL-3-HYDROXYPYRIDINE
  • 6-METHYL-3-PYRIDINOL
  • 3-HYDROXY-6-METHYLPYRIDINE
CAS:
1121-78-4
MF:
C6H7NO
MW:
109.13
EINECS:
214-337-8
Product Categories:
  • Heterocycle-Pyridine series
  • Pyridine
  • Pyridine Series
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Heterocycles
Mol File:
1121-78-4.mol
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3-Hydroxy-6-methylpyridine Chemical Properties

Melting point:
168-170 °C(lit.)
Boiling point:
204.59°C (rough estimate)
Density 
1.1143 (rough estimate)
refractive index 
1.5040 (estimate)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
dichloromethane: soluble
pka
9.49±0.10(Predicted)
form 
Crystalline Powder
color 
Beige to light tan
BRN 
107077
InChIKey
DHLUJPLHLZJUBW-UHFFFAOYSA-N
LogP
0.418 (est)
CAS DataBase Reference
1121-78-4(CAS DataBase Reference)
NIST Chemistry Reference
3-Pyridinol, 6-methyl-(1121-78-4)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-37/38-41-40-36/37/38
Safety Statements 
26-39-24/25-36-22
WGK Germany 
3
RTECS 
UU7714900
HS Code 
29333990
Toxicity
mouse,LD50,intraperitoneal,846mg/kg (846mg/kg),Toxicon. Vol. 23, Pg. 815, 1985.

MSDS

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3-Hydroxy-6-methylpyridine Usage And Synthesis

Chemical Properties

beige to light tan crystalline powder

Uses

  • 5-Hydroxy-2-methylpyridine was used as starting reagent for the synthesis of 5-[(4-methoxybenzyl)oxy]-2-pyridinecarbaldehyde.
  • It was used in synthesis of [HNC6H6OH]2[Cu(NC5H5)4(NbOF5)2].
  • It was used as ligand of a platinum complex which showed protein kinase inhibitory action at nanomolar levels.
  • It forms a chiral pyridinium ionic liquid on reaction with L-menthol chloromethyl ether.

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