Methoxypolyethylene glycols Chemical Properties

Melting point:

60-64 °C

Boiling point:

>200°C/760mmHg

Density 

1.094 g/mL at 25 °C

vapor density 

>1 (vs air)

vapor pressure 

0.05 mm Hg ( 20 °C)

refractive index 

n20/D 1.459

Flash point:

268 °C

storage temp. 

-20°C

solubility 

H₂O: 50 mg/mL at 25 °C, clear, colorless

form 

semisolid

Specific Gravity

1.094

color 

White to pale yellow

PH

5.5-7.0 (25℃, 50mg/mL in H2O)

Water Solubility 

Slightly miscible with water.

λmax

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

Stability:

Stable. Incompatible with strong oxidizing agents, strong acids, strong bases.

InChIKey

XNWFRZJHXBZDAG-UHFFFAOYSA-N

LogP

-0.800 (est)

EPA Substance Registry System

Poly(oxy-1,2-ethanediyl), .alpha.-methyl-.omega.-hydroxy- (9004-74-4)

Safety Information

Safety Statements 

24/25-22

WGK Germany 

3

RTECS 

PE8271000

F 

3

TSCA 

Yes

HS Code 

29091990

MSDS

• Language:English Provider:Methoxypolyethylene glycols
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Methoxypolyethylene glycols Usage And Synthesis

Description

m-PEG36-alcohol is a PEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.

Chemical Properties

varies from viscous liquid to white flakes, depending

Uses

enteric coating controlled release and enteric release coatings

Uses

Methoxypolyethylene Glycol of with an average molecular mass of 350. Methoxypolyethylene Glycol (MPEG) is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.

Uses

Methoxypolyethylene glycol 350 has been used in a study to assess the synthesis of a new class of thermosensitive micellar cyclotriphosphazenes. It has also been used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.

Definition

ChEBI: A poly(ethylene glycol) terminated with a methyl group at one end.

brand name

Carbowax Sentry Methoxypolyethylene Glycol (Union Carbide).

General Description

It is a Polyethylene glycol (PEG) macromer with a reactive chain end consisting of methyl ether. Etherification of the PEG chain ends can be undertaken in basic conditions by reacting it with alkyl halides. mPEG can undergo cross linking to form hydrogels; polymerization can be initiated by redox reaction or free radical initiator.

Solubility in organics

Acetone, chloroform, cyclohexanone, dichloromethane, DMF, MEK, toluene (hot), water

Methoxypolyethylene glycols(9004-74-4)Related Product Information

• ETHYLENE OXIDE
• Ethylene carbonate
• Diethylene glycol monomethyl ether
• Ethylene glycol diacetate
• Ethylene glycol
• Polyethylene glycol dimethyl ether
• ETHYLENE DIACRYLATE
• TRIETHYLENE GLYCOL MONOMETHYL ETHER
• 2-Methoxyethanol
• Triethylene glycol dimethyl ether
• 1,2-Dimethoxyethane
• 1,2-Dibromoethane
• C8E3
• ETHYLENE
• POLY(ETHYLENE GLYCOL) METHYL ETHER METHACRYLATE
• Polyethylene Glycol
• O-Phenylphenoxyethyl Acrylate
• PROPYLENE GLYCOL