4-(Trifluoromethylthio)phenol Chemical Properties

Melting point:

57-60 °C (lit.)

Boiling point:

77-78 °C/7 mmHg (lit.)

Density 

1.45

Flash point:

57°C

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

soluble in Methanol

form 

powder to crystal

pka

8.53±0.13(Predicted)

color 

White to Almost white

Sensitive 

Stench

InChIKey

YYCPTWHVKSATQK-UHFFFAOYSA-N

CAS DataBase Reference

461-84-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HazardClass 

IRRITANT, STENCH

HS Code 

2930909899

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-(Trifluoromethylthio)phenol Usage And Synthesis

Chemical Properties

Colorless or light yellow crystalline

Uses

4-(Trifluoromethylthio)phenol may be used in the preparation of phenylamino derivative, which is an important intermediate in the synthesis of toltrazuril.

General Description

4-(Trifluoromethylthio)phenol undergoes reaction with NBS (N-Bromosuccinimide), NIS (N-Iodosuccinimide), HNO₃, HNO₃/H₂SO₄ and 4-bromobenzyl bromide to afford bromo-, iodo-, nitro- and benzyl substituted products.

4-(Trifluoromethylthio)phenol(461-84-7)Related Product Information

• Nonylphenol
• Cresol
• p-Cresol
• 4-Fluorophenol
• Phenol Red
• Guaiacol
• 3-Aminophenol
• 4-Trifluoromethylphenol
• Phenol
• 4-(TRIFLUOROMETHYLTHIO)BENZOIC ACID
• 4-(TRIFLUOROMETHYLTHIO)BENZALDEHYDE
• 4-Hydroxydiphenylamine
• 4-(Trifluoromethyl)cinnamic acid
• Trifluoro-p-tolunitrile
• 4-(Trifluoromethyl)benzenesulfonamide
• 4'-(Trifluoromethyl)acetophenone
• p-Trifluoromethoxy phenol
• 4-(Trifluoromethyl)benzaldehyde