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Tolnapersine

Basic information Safety Supplier Related

Tolnapersine Basic information

Product Name:
Tolnapersine
Synonyms:
  • TOLNAPERSINE
  • BK 34-530
  • 6-[4-(2-Methylphenyl)-1-piperazinyl]-5,6,7,8-tetrahydro-2-naphthol
  • 6-(4-(2-Methylphenyl)-1-piperazinyl)-5,6,7,8-tetrahydronaphthalen-2-ol
  • 2-Naphthalenol, 5,6,7,8-tetrahydro-6-[4-(2-methylphenyl)-1-piperazinyl]-
  • Tolnapersine ISO 9001:2015 REACH
CAS:
70312-00-4
MF:
C21H26N2O
MW:
322.44
Mol File:
70312-00-4.mol
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Tolnapersine Usage And Synthesis

Uses

Tolnapersine exhibits multidrug resistance (MDR) reversal activity, which reverses the resistance of tumor cells to multiple chemotherapy drugs by affecting P-glycoprotein (Pgp) on the cell membrane[1].

References

[1] Ramu A, et al., Reversal of multidrug resistance by bis(phenylalkyl)amines and structurally related compounds. Cancer Chemother Pharmacol. 1994;34(5):423-30. DOI:10.1007/BF00685568

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