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5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone

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5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone Basic information

Product Name:
5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone
Synonyms:
  • 4H-1-Benzopyran-4-one,5-(b-D-glucopyranosyloxy)-7-hydroxy-2-(4-hydroxyphenyl)-
  • 5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone
  • Apigenin 5-glucoside
  • Apigenin 5-O-beta-D-glucopyraside
  • Apigenin 5-O-beta-D-glucopyranoside
  • Apigenin 5-O-glucoside
  • Apigenin 5-O-β-D-glucopyranoside
  • 7-Hydroxy-2-(4-hydroxyphenyl)-5-((2S,3S,4S,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one
CAS:
28757-27-9
MF:
C21H20O10
MW:
432.38
Mol File:
28757-27-9.mol
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5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone Chemical Properties

Melting point:
226-227 °C
Boiling point:
814.2±65.0 °C(Predicted)
Density 
1.642±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Methanol
form 
powder
pka
6.44±0.40(Predicted)
color 
Yellow
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5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone Usage And Synthesis

Uses

Apigenin 5-O-β-D-Glucopyranoside is an intermediate in synthesizing Apigenin 5-O-β-D-Glucuronide (A426510), a metabolite of Apigenin (A726500), Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap junction intracellular communication in liver cells.

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