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4,8-Dimethoxyfuro[2,3-b]quinolin-7-ol

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4,8-Dimethoxyfuro[2,3-b]quinolin-7-ol Basic information

Product Name:
4,8-Dimethoxyfuro[2,3-b]quinolin-7-ol
Synonyms:
  • 4,8-Dimethoxyfuro[2,3-b]quinolin-7-ol
  • Haplopine
  • Furo(2,3-B)quinolin-7-ol, 4,8-dimethoxy-
  • Heliparvifoline
  • 7-Hydroxy-8-methoxydictamnine
CAS:
5876-17-5
MF:
C13H11NO4
MW:
245.23
Mol File:
5876-17-5.mol
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4,8-Dimethoxyfuro[2,3-b]quinolin-7-ol Chemical Properties

Melting point:
202-204 °C
Boiling point:
431.2±40.0 °C(Predicted)
Density 
1.361±0.06 g/cm3(Predicted)
pka
5.60±0.30(Predicted)
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Safety Information

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
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4,8-Dimethoxyfuro[2,3-b]quinolin-7-ol Usage And Synthesis

Description

A further Haplophyllum alkaloid, this base occurs in H. perforatum (MB) Kar. et Kir. and in H. robustum Bge. It crystallizes as small colourless needles from MeOH and has been characterized as the crystalline hydrochloride, m.p. 168- 9°C. The base may be isomerized to isohaplopine, which forms colourless rods from MeOH with m.p. 170-2°C.

Definition

ChEBI: Haplopine is an oxacycle, an organonitrogen heterocyclic compound and an organic heterotricyclic compound.

References

Sidyakin, Yunusov, Dokl. Akad. Nauk. Uzbek SSR, 4, 39 (1962)
Fakhritdinova, Sidyakin, Yunusov,Khim.Prir. Soedin., 1, 107 (1965)

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