Dazomet Chemical Properties

Melting point:

104-105°C

Boiling point:

222.3±50.0 °C(Predicted)

Density 

1.3

vapor pressure 

3.7 x 10^-4 Pa (25 °C)

refractive index 

1.5005 (estimate)

Flash point:

156 °C

storage temp. 

0-6°C

solubility 

Chloroform (Slightly), DMSO (Slightly)

pka

4.04±0.20(Predicted)

Water Solubility 

<0.1 g/100 mL at 18 ºC

Merck 

13,2854

BRN 

116039

InChIKey

QAYICIQNSGETAS-UHFFFAOYSA-N

LogP

1.400

CAS DataBase Reference

533-74-4(CAS DataBase Reference)

NIST Chemistry Reference

2H-1,3,5-thiadiazine-2-thione, tetrahydro-3,5-dimethyl-(533-74-4)

EPA Substance Registry System

Dazomet (533-74-4)

Safety Information

Hazard Codes 

Xn,N

Risk Statements 

22-36-50/53

Safety Statements 

15-22-24-60-61

RIDADR 

UN3077 9/PG 3

WGK Germany 

3

RTECS 

XI2800000

HazardClass 

6.1

PackingGroup 

III

HS Code 

29349990

Hazardous Substances Data

533-74-4(Hazardous Substances Data)

Toxicity

LD50 in rats, mice, guinea pigs, rabbits (g/kg): 0.32-0.62, 0.18, 0.16, 0.12 orally; in rats, rabbits, dogs (g/kg): 0.087, 0.127, 0.047-0.063 i.p.; in rabbits (g/kg): 7.1 dermally (Smyth)

Dazomet Usage And Synthesis

Description

Dazomet is a biocide used to control bacterial and fungal growth in pulp and paper systems, but also in agriculture for soil disinfection. It is contained in Busan 1058, Mylone and Fungicide 974 (Crag). Sensitization, rarely reported, occurred in a paper-mill worker.

Chemical Properties

White crystalline solid. Nearly odorless.

Uses

Dazomet is a as fumigant used for the control of brown root rot disease. Dazomet was shown to be a possible agent in preventing pest incursion in agriculture, gardening and agroforestry.

Uses

Soil fungicide, nematocide, weed killer; slimicide in paper making.

Uses

Dazomet is a multi-purpose soil fumigant used for the control of nematodes, soil fun@, soil insects and weed seeds. It is also used as a slimicide in pulp and paper manufacture and as a preservative of adhesives.

Uses

Soil fungicide; nematocide; herbicide; insecticide; soil sterilant.

Definition

ChEBI: A dithiocarbamic ester that is 1,3,5-thiadiazinane with a thione moiety at position 2 and in which the hydrogens attached to the nitrogens are replaced by methyl groups. A fungicide, herbicide and nematicide, it is used prior to sowing or planting for the ontrol of soil fungi, nematodes, bacteria and germinating weeds, and as fumigant for poultry litter and eggs to control Salmonella. It is a non-ozone-depleting alternative to methyl bromide.

General Description

White crystals or off-white powder. Pungent, acrid odor.

Air & Water Reactions

Insoluble in water. Slowly hydrolyzed.

Reactivity Profile

Dazomet decomposes in water, dilute acids and alcohol.

Fire Hazard

Flash point data for Dazomet are not available; however, Dazomet is probably combustible.

Contact allergens

Dazomet is a biocide used to control bacterial and fungal growth in a pulp and paper system, and also in agriculture for soil disinfection. It is contained in Busan 1058, Mylone, and Fungicide 974 (Crag?). Sensitization, rarely reported, occurred in a paper mill worker.

Safety Profile

Poison bj 7 in ' g estion and intraperitoneal routes. Moderately toxic by skin contact and subcutaneous routes. A severe eye irritant. A mild primary skin irritant and sensitizer. When heated to decomposition it emits very toxic fumes of NOx and SOx

Potential Exposure

Dazomet is a dithiocarbamate insecti- cide, herbicide, fumigant, fungicide, nematicide. It is used as a soil fumigant used against germinating weed seeds, soil insects, nematodes, and soil-borne diseases in forest nursery seed beds, tobacco crops, greenhouse crops, and substrates for potted plants, turf, and ornamentals. It is also used as an antimicrobial agent for slimicide preparations and for adhesives, paper-mill slimicide, paint, and cooling water slimicides.

Environmental Fate

Soil. Soil metabolites include formaldehyde, hydrogen sulfide, methylamine and methyl(methylaminomethyl)dithiocarbamic acid (Hartley and Kidd, 1987) which further decomposes to methyl isothiocyanate (Harley and Kidd, 1987; Ashton and Monaco, 1991; Cremlyn, 1991). The rate of decomposition is dependent upon the soil type, temperature and humidity (Cremlyn, 1991).
Chemical/Physical. Hydrolyzes in acidic solutions forming carbon disulfide, methylamine and formaldehyde (Hartley and Kidd, 1987; Humburg et al., 1989). These compounds are probably formed following the decomposition of dazomet with alcohol and

Metabolic pathway

Dazomet is a propesticide that decomposes to generate the highly volatile methyl isothiocyanate. The pathways of metabolism of methyl isothiocyanate are described under its own entry. In soil, dazomet degrades mainly via a dithiocarbamic acid which in turn affords methyl isothiocyanate, formaldehyde, hydrogen sulfide and methy lamine.

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

Degradation

Dazomet is rapidly hydrolysed in acidic media to carbon disulfide, formaldehyde and methylamine (PM). DT₅₀ values for hydrolysis were 85, 490 and 110 hours at pH 5,7 and 9, respectively. It is sensitive to oxygen and to light.

Incompatibilities

Sensitive to moisture and heat. Decomposes on heating above 102 C, producing toxic fumes including nitrogen oxides and sulfur oxides. Dithiocarbamate esters are combustible. They react vio- lently with powerful oxidizers such as calcium hypochlo- rite. Poisonous gases are generated by the thermal decomposition of Dithiocarbamate compounds, including carbon disulfide, oxides of sulfur, oxides of nitrogen, hydrogen sulfide, ammonia, and methylamine. Thio and dithiocarbamates slowly decompose in aqueous solution to form carbon disulfide and methylamine or other amines. Such decompositions are accelerated by acids. Flammable gases are generated by the combination of dithiocarbamate with aldehydes, nitrides, and hydrides. Dithiocarbamate are incompatible with acids, peroxides, and acid halides.

Waste Disposal

Do not discharge into drains or sewers. Dispose of waste material as hazardous waste using a licensed disposal contractor to an approved landfill. Consult with environmental regulatory agencies for guid- ance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. A potential candidate for liquid injection incineration at a temperature range of 650℃ to 1600℃ and a residence time 0.1 to 2 seconds. Also, a potential candidate for rotary kiln incineration at a temperature range of 820℃ to 1600℃ and residence times of seconds for liquids and gases, and hours for solids .In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

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