1,2,9,10-TETRACHLORODECANE Chemical Properties

Boiling point:

335.7±10.0 °C(Predicted)

Density 

1.167±0.06 g/cm3(Predicted)

1,2,9,10-TETRACHLORODECANE Usage And Synthesis

Biological Activity

1,2,9,10-Tetrachlorodecane is a cyclic peptide that inhibits the JmjC histone demethylases KDM4 with IC50s of 42 nM and 29 nM for KDM4A and KDM4C, respectively.

in vitro

1,2,9,10-Tetrachlorodecane specifically binds to the KDM4A substrate binding pocket. It binds to the KDM4A active site competitively with histone substrates.

target

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