2,2-DIMETHYL-1,3-DIOXAN-5-AMINE Chemical Properties

Boiling point:

169.0±35.0 °C(Predicted)

Density 

0.975±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

7.02±0.40(Predicted)

2,2-DIMETHYL-1,3-DIOXAN-5-AMINE Usage And Synthesis

Uses

2,2-Dimethyl-1,3-dioxan-5-amine is used as a reactant in the preparation of 5-phenylamino-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione series of MEK inhibitors, and discovery of TAK-733, a potent and selective MEK allosteric site inhibitor and treatment of cancer.

2,2-DIMETHYL-1,3-DIOXAN-5-AMINE(40137-24-4)Related Product Information

• DIMETHYLMERCURY
• 2,2-DIMETHYL-5-NITRO-1,3-DIOXANE
• 12-KETOSTEARIC ACID 2-AMINO-2-METHYLPROPAN-1-OL KETAL
• (4S,5S)-(+)-2,2-DIMETHYL-5-METHYLAMINO-4-PHENYL-1,3-DIOXANE
• (5-AMINO-2,2-DIMETHYL-[1,3]DIOXAN-5-YL)-METHANOL
• KIFUNENSINE DIACETONIDE
• 2-Deoxy-1,3:4,5-di-O-isopropylidene-2-oxamoylamino-D-mannitol
• 2,2-DIMETHYL-1,3-DIOXAN-5-AMINE
• 5-AMINO-2,2-DIMETHYL-1,3-DIOXANE-5-METHANOL OXALATE (2:1)
• 2,2-DIMETHYL-5-NITRO-1,3-DIOXANE-5-METHANOL
• METHYL 3-((4,4-DIMETHYL-2,6-DIOXO(3,5-DIOXANYL))DIAZENYL)-5-NITROBENZO[B]THIOPHENE-2-CARBOXYLATE
• AKOS 367
• 5-{[4,6-bis(1-aziridinyl)-1,3,5-triazine-2-yl]amino]-2-2-dimehtyl-1,3-dioxane-5-methanol
• 5-((4-(3-CHLORO-5-(TRIFLUOROMETHYL)(2-PYRIDYLTHIO))PHENYL)DIAZENYL)-2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE
• AURORA KA-5313
• 5-((3,4-DICHLOROPHENYL)DIAZENYL)-2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE
• 2,2-DIMETHYL-4,4A,6,8A-TETRAHYDRO-[1,3]DIOXINO[5,4-B]PYRIDINE-5-CARBOXYLIC ACID TERT-BUTYL ESTER