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4-Trifluoromethylsalicylic acid

Basic information Safety Supplier Related

4-Trifluoromethylsalicylic acid Basic information

Product Name:
4-Trifluoromethylsalicylic acid
Synonyms:
  • 4-(Trifluoromethyl)salicylic acid, 2-Carboxy-5-(trifluoromethyl)phenol, 4-Carboxy-3-hydroxybenzotrifluoride
  • 4-(TrifluoroMethyl)salicylic acid, water ≤0.3%
  • α,α,α-Trifluoro-2,4-cresotic Acid
  • 4- threefluorine Methylsalicylate
  • 4-(TrifluoroMethyl)benzoic Acid, 97+%
  • p-Trifluoromethylsalicylicacid
  • 4-(TRIFLUOROMETHYL)SALICYLIC ACID
  • 2-HYDROXY-4-(TRIFLUOROMETHYL)BENZOIC ACID
CAS:
328-90-5
MF:
C8H5F3O3
MW:
206.12
EINECS:
700-368-9
Product Categories:
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • Aromatics
  • Pharmaceuticals
  • 328-90-5
Mol File:
328-90-5.mol
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4-Trifluoromethylsalicylic acid Chemical Properties

Melting point:
178 °C
Boiling point:
286.4±40.0 °C(Predicted)
Density 
1.539±0.06 g/cm3(Predicted)
vapor pressure 
0.013-0.076Pa at 25℃
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
2.45±0.10(Predicted)
form 
Solid
color 
White to Off-White
InChIKey
XMLFPUBZFSJWCN-UHFFFAOYSA-N
LogP
3.21
CAS DataBase Reference
328-90-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
29189900
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4-Trifluoromethylsalicylic acid Usage And Synthesis

Chemical Properties

White to off-white solid

Uses

The active metabolite of Triflusal; inhibits cardiac hypertrophy in vitro and in vivo by blocking the NF-κB signaling pathway.

Definition

ChEBI: 2-Hydroxy-4-trifluoromethyl benzoic acid is a hydroxybenzoic acid. It is functionally related to a salicylic acid.

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