7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE
7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE Basic information
- Product Name:
- 7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE
- Synonyms:
-
- STO-609, >98%
- STO609;STO 609
- STO-609 - CAS 52029-86-4 - Calbiochem
- STO-609 free base
- STO-609
- STO-609 ACETATE
- STO-609 ACETIC ACID
- 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid - acetic acid
- CAS:
- 52029-86-4
- MF:
- C19H10N2O3
- MW:
- 314.29
- Product Categories:
-
- Protein Kinase
- Mol File:
- 52029-86-4.mol
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7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE Chemical Properties
- Melting point:
- >300 °C
- Boiling point:
- 716.9±62.0 °C(Predicted)
- Density
- 1.54±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO: 15 mg/mL at ≥60 °C
- form
- solid
- pka
- 2.65±0.20(Predicted)
- color
- Light yellow to yellow
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
MSDS
- Language:English Provider:SigmaAldrich
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7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE Usage And Synthesis
Uses
7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid is a calcium/calmodulin-dependent protein kinase inhibitor and was found to upregulate various AhR target genes in human macrophages.
Definition
ChEBI: LSM-3164 is a naphthoic acid.
Biological Activity
Selective, cell-permeable inhibitor of Ca 2+ -calmodulin-dependent protein kinase kinase (K i values are 80 and 15 ng/ml for inhibition of CaM-KK α and CaM-KK β respectively); competes for the ATP-binding site. Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK.
7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATESupplier
J & K SCIENTIFIC LTD.
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- 010-82848833 400-666-7788
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3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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- 025-66099280 17798518460
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MedChemexpress LLC
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- 021-58955995
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Guangzhou Isun Pharmaceutical Co., Ltd
- Tel
- 020-39119399 18927568969
- isunpharm@qq.com
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7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE(52029-86-4)Related Product Information
- ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate
- Isoquinoline-3-carboxylic acid
- 1H-BENZIMIDAZOLE, 2-(1-NAPHTHALENYL)-
- 4-(1H-Benzoimidazol-2-yl)-benzoic acid
- AURORA KA-3763
- 2-NAPHTHALEN-1-YL-1H-IMIDAZOLE
- 1-ACETYL-2-METHYLBENZIMIDAZOLE
- 1-METHYL-2-NAPHTHALEN-1-YL-1H-IMIDAZOLE
- BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
- 4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID
- 7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE