7-Nitro-1,2,3,4-tetrahydroquinoline Chemical Properties

Melting point:

61.0 to 65.0 °C

Boiling point:

325.2±31.0 °C(Predicted)

Density 

1.236±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

soluble in Methanol

pka

3.44±0.20(Predicted)

form 

Powder

color 

Red

CAS DataBase Reference

30450-62-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

T

Risk Statements 

25

Safety Statements 

45

RIDADR 

UN 2811 6.1 / PGIII

HS Code 

2933499090

7-Nitro-1,2,3,4-tetrahydroquinoline Usage And Synthesis

Uses

7-Nitro-1,2,3,4-tetrahydroquinoline is a quinoline compound that can be used as a reagent in chemical reactions or as an intermediate in organic synthesis. It can be used to prepare 7-Aminoquinoline and 7-Nitroquinoline.

Synthesis

7-Nitro-1,2,3,4-tetrahydroquinoline is synthesised by the reaction of 1,2,3,4-tetrahydroquinoline and nitric acid in sulphuric acid solution. The specific synthesis steps are as follows:
Concentrated sulfuric acid (30.00 mL) was cooled to -10° C. with an ice/salt bath. To this, 1,2,3,4-tetrahydro-quinoline (10.60 g, 75.60 mmol) and a solution of nitric acid (99.5percent, 4.80 g, 75.60 mmol) in sulfuric acid (15.00 mL) were added simultaneously within 1 hour, so that the temperature of the reaction mixture does not exceed 10° C. The mixture was stirred then for 2.5 hours at -5° C., then poured over ice and treated with sodium carbonate (0.10 kg) until pH 8-9 was reached. The solid was filtered, washing with water, then dissolved in dichloromethane. The organic phase was washed with water, dried over magnesium sulphate and evaporated. 7-Nitro-1,2,3,4-tetrahydro-quinoline was obtained as a viscous brown oil, 13.70 g (85percent), 84percent purity.

7-Nitro-1,2,3,4-tetrahydroquinoline(30450-62-5)Related Product Information

• Isoquinoline
• Quinoline Yellow
• Quinclorac
• Ethoxyquin
• Quinhydrone
• 1,2,3,4-Tetrahydroquinoline
• 5,6,7,8-TETRAHYDROISOQUINOLINE
• 8-Hydroxyquinoline
• N-Ethyl-7-nitro-1,2,3,4-tetrahydroquinoline ,98%,1-Ethyl-7-nitro-1,2,3,4-tetrahydroquinoline
• 1-Methyl-7-nitro-1,2,3,4-tetrahydroquinoline
• NITROGEN DIOXIDE
• 6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinolin
• 1-(2-Methylpropyl)-7-nitro-1,2,3,4-tetrahydroquinoline
• N-ETHYL-7-NITRO-1,2,3,4-TETRAHYDROQUINOLINE
• 7-NITRO-QUINOLINE
• QUINOLINE HYDROCHLORIDE
• 6-NITRO-1,2,3,4-TETRAHYDROQUINOLINE
• 7-Nitro-1,2,3,4-tetrahydroquinoline