ALPHA-PHENYL-1-(2-PHENYLETHYL)-4-PIPERIDINEMETHANOL Chemical Properties

Melting point:

125-128 °C

Boiling point:

434.2±20.0 °C(Predicted)

Density 

1.084±0.06 g/cm3(Predicted)

storage temp. 

Store at RT

solubility 

DMSO: ≥8mg/mL

form 

powder

pka

14.13±0.20(Predicted)

color 

white to tan

Safety Information

Hazard Codes 

N

Risk Statements 

50/53

Safety Statements 

60-61

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

ALPHA-PHENYL-1-(2-PHENYLETHYL)-4-PIPERIDINEMETHANOL Usage And Synthesis

Uses

MDL 11,939 is a potent and selective SR-2 antagonist. It can also be used to treat psychological and brain disorders.

Definition

ChEBI: Phenyl-[1-(2-phenylethyl)-4-piperidinyl]methanol is a primary amine.

Biological Activity

Potent, selective and orally active 5-HT 2 receptor antagonist (K i values are 0.54 and 81.6 nM at 5-HT 2A and 5-HT 2C receptors respectively).

storage

Store at RT

ALPHA-PHENYL-1-(2-PHENYLETHYL)-4-PIPERIDINEMETHANOL(107703-78-6)Related Product Information

• (R)-(+)-ALPHA-(3-HYDROXY-2-METHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL
• (-)-MDL 100907
• ALPHA-PHENYL-1-(2-PHENYLETHYL)-4-PIPERIDINEMETHANOL
• Volinanserin Hydrochloride Salt
• (+/-)-ALPHA-(2,3-DIMETHOXY-PHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINE-METHANOL
• (-)-MDL 105725