ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Standard Substance > PROTRIPTYLINE HYDROCHLORIDE
PROTRIPTYLINE HYDROCHLORIDE
PROTRIPTYLINE HYDROCHLORIDE Basic information
- Product Name:
- PROTRIPTYLINE HYDROCHLORIDE
- Synonyms:
-
- concordin
- d)cyclohepten-5-propylamine,n-methyl-5h-dibenzo(hydrochloride
- maximed
- mk-240
- n-methyl-5h-dibenzo(a,d)cycloheptene-5-propylaminehydrochloride
- normethylex4442
- triptilhydrochloride
- Protriptylin hydrochloride
- CAS:
- 1225-55-4
- MF:
- C19H22ClN
- MW:
- 299.84
- EINECS:
- 214-956-3
- Product Categories:
-
- Biogenic Amine Transport Inhibitors
- Biogenic Amine Transport InhibitorsObesity Research
- Neurotransmission
- Neurotransmission (Obesity)
- Neurotransmitters
- Mol File:
- 1225-55-4.mol
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PROTRIPTYLINE HYDROCHLORIDE Chemical Properties
- Melting point:
- 169-171°
- Flash point:
- 9℃
- storage temp.
- 2-8°C
- solubility
- H2O: soluble50mg/mL
- pka
- 8.2(at 25℃)
- form
- powder
- color
- white to off-white
- Water Solubility
- H2O: 50mg/mL
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-10,12-13,19-20H,6,11,14H2,1H3;1H
- InChIKey
- OGQDIIKRQRZXJH-UHFFFAOYSA-N
- SMILES
- C1(CCCNC)C2C=CC=CC=2C=CC2C=CC=CC1=2.Cl
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Safety Information
- Hazard Codes
- Xn,T,F
- Risk Statements
- 20/21/22-36/37/38-39/23/24/25-23/24/25-11
- Safety Statements
- 26-36-45-36/37-16-7
- RIDADR
- 3249
- WGK Germany
- 3
- RTECS
- HP1400000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 2921490002
- Toxicity
- dog,LDLo,oral,400mg/kg (400mg/kg),"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 88, 1972.
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PROTRIPTYLINE HYDROCHLORIDE Usage And Synthesis
Uses
Monoamine reuptake inhibitor; tricyclic antidepressant.
brand name
Vivactil (Odyssey).
General Description
Protriptyline hydrochloride, N-methyl-5H-dibenzo[a,d]-cycloheptene-5-propylamine hydrochloride, 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene hydrochloride(Vivactil), like the other compounds under consideration, isan effective antidepressant. The basis for its chemical namingcan be seen by consulting the naming and the structureof imipramine. Protriptyline is a structural isomer of nortriptyline.Inactivation can be expected to involve the relativelylocalized double bond. Because it is a monomethylcompound, its sedative potential is low.
Biochem/physiol Actions
Norepinephrine uptake blocker.
PROTRIPTYLINE HYDROCHLORIDESupplier
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