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rac a-Hydroxy Ibuprofen

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rac a-Hydroxy Ibuprofen Basic information

Product Name:
rac a-Hydroxy Ibuprofen
Synonyms:
  • α-Ηydroxy-α-Methyl-4-(2-Methylpropyl)benzeneacetic Acid
  • 2-hydroxy-2-(4-isobutylphenyl)propanoic acid
  • IBuprofen Impurity 13
  • Ibuprofen EP Impurity M
  • Imp. M (EP): (2RS)-2-Hydroxy-2-[4-(2-methylpropyl)phenyl]propanoic Acid
  • rac α-Hydroxy Ibuprofen(Ibuprofen EP Impurity M)
  • Ibuprofen impurity 7/Ibuprofen EP Impurity M/rac a-Hydroxy Ibuprofen/2-hydroxy-2-(4-isobutylphenyl)propanoic acid
  • Ibuprofen-9
CAS:
60057-62-7
MF:
C13H18O3
MW:
222.28
Product Categories:
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
60057-62-7.mol
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rac a-Hydroxy Ibuprofen Chemical Properties

Melting point:
95-97°C
Boiling point:
367.9±27.0 °C(Predicted)
Density 
1.122±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
3.62±0.25(Predicted)
color 
White to Off-White
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rac a-Hydroxy Ibuprofen Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

A potential precursor of Ibuprofen and Naproxen. Antiinflammatory agent.

Synthesis Reference(s)

The Journal of Organic Chemistry, 60, p. 742, 1995 DOI: 10.1021/jo00108a047

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