4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Chemical Properties

Melting point:

148 - 150°C

Boiling point:

538.6±60.0 °C(Predicted)

Density 

1.258

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), DMSO (Slightly)

form 

Solid

pka

2.70±0.12(Predicted)

color 

Pale Yellow to Light Beige

Safety Information

HS Code 

2916399090

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Usage And Synthesis

Uses

Methyl 4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate is an intermediate used in the synthesis of 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide (M326838), which is an impurity of Nilotinib (N465300), a possible agent in the treatment of chronic myelogenous leukemia.

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester(917392-54-2)Related Product Information

• NILOTINIB IMPURITY 11
• 4-Methyl-N-(3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)phenyl)-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzaMide
• 3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)benzenaMine
• 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate
• 1H-IMidazole, 4-Methyl-1-[3-nitro-5-(trifluoroMethyl)phenyl]-
• 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile
• 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid
• Benzenamine, 3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)-
• Methyl 3-amino-4-methylbenzoate
• Nilotinib Impurity 10
• Nilotinib N-Oxide
• Nilotinib Impurity 7
• Nilotinib genotoxic impurity 3
• Nilotinib Impurity 1
• Nilotinib Impurity 20
• 3-Amino-4-methylbenzoic acid
• Nilotinib Impurity 28
• Nilotinib impurity 3