Hirsutal Chemical Properties

Boiling point:

679.6±55.0 °C(Predicted)

Density 

1.362±0.06 g/cm3(Predicted)

pka

9.76±0.10(Predicted)

Hirsutal Usage And Synthesis

Uses

Hirsutanonol ((5S)-Hirsutanonol) is a diarylheptanoid that can be isolated from the bark of Alnus hirsute var. sibirica. Hirsutanonol inhibits cyclooxygenase-2 (COX-2) expression. Hirsutanonol has anti-filarial with an IC50 value of 44.11 μg/mL for microfilariae[1].

References

[1] Lee MW, et al. Inhibition of cyclooxygenase-2 expression by diarylheptanoids from the bark of Alnus hirsuta var. sibirica. Biol Pharm Bull. 2000 Apr;23(4):517-8. DOI:10.1248/bpb.23.517
[2] Yadav D, et al. Antifilarial diarylheptanoids from Alnus nepalensis leaves growing in high altitude areas of Uttarakhand, India. Phytomedicine. 2013 Jan 15;20(2):124-32. DOI:10.1016/j.phymed.2012.10.017

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