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D-Lysine

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D-Lysine Basic information

Product Name:
D-Lysine
Synonyms:
  • D-2,6-DIAMINOHEXANOIC ACID
  • (R)-2,6-DIAMINOCAPROIC ACID
  • (R)-2,6-Diaminohexanoic acid
  • D-LYSINE
  • D-LYSIN
  • D-LysineBase
  • (2R)-2,6-diaminohexanoic acid
  • (R)-Lysine
CAS:
923-27-3
MF:
C6H14N2O2
MW:
146.19
EINECS:
213-091-9
Product Categories:
  • Amino acid
  • chiral
  • Amino Acids
Mol File:
923-27-3.mol
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D-Lysine Chemical Properties

Melting point:
218 °C (dec.)(lit.)
Boiling point:
311.5±32.0 °C(Predicted)
Density 
1.125±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
H2O: soluble
pka
2.49±0.24(Predicted)
form 
Solid
color 
Off-White to Pale Beige
optical activity
-25.2493°(C=1.0028g/ml 6N HCL)
Water Solubility 
H2O: soluble
BRN 
1722530
InChI
InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m1/s1
InChIKey
KDXKERNSBIXSRK-RXMQYKEDSA-N
SMILES
C(O)(=O)[C@@H](CCCCN)N
LogP
-0.734 (est)
CAS DataBase Reference
923-27-3(CAS DataBase Reference)
EPA Substance Registry System
D-Lysine (923-27-3)
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Safety Information

WGK Germany 
3
HS Code 
29224999

MSDS

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D-Lysine Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

D-Lysine is the unnatural isomer of L-Lysine (L468895) that has the ability to reduce non-enzymatic glycation in vitro. D-Lysine also exists as polypeptide chains of poly-D-lysine, a nonspecific adhesion-promoting molecule that has the potential to be a polymeric drug carrier.

Uses

D-Lysine is used as a component of a wide array of polymers (poly-D-lysine), surfactants and biofilms to confer a positive (cationic) charge.

Definition

ChEBI: D-lysine is the D-enantiomer of the alpha-amino acid lysine. It has a role as a bacterial metabolite and a fungal metabolite. It is a lysine and a D-alpha-amino acid. It is a conjugate base of a D-lysinium(1+). It is a conjugate acid of a D-lysinate. It is an enantiomer of a L-lysine.

in vivo

D-Lysine (400 mg/kg; i.v. or p.o.) dose not result in significantly greater inhibition of kidney uptake of '"In-DTPAOC, and Oral administration of D-lysine also reduces kidney uptake in rats[1].

IC 50

Human Endogenous Metabolite

D-Lysine Supplier

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