H2N-PEG8-tBu Chemical Properties

Boiling point:

544.3±45.0 °C(Predicted)

Density 

1.067±0.06 g/cm3(Predicted)

storage temp. 

2-8°C(protect from light)

solubility 

Soluble in Water, DMSO, DCM, DMF

form 

Oil

pka

8.74±0.10(Predicted)

Safety Information

HS Code 

2942000090

H2N-PEG8-tBu Usage And Synthesis

Description

Amino-PEG8-t-butyl ester is a monodisperse PEG linker containing an amino group with a t-butyl protected carboxyl group.The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

H2N-PEG8-tBu is a cleavable 8-unit PEG-ADC linker for antibody drug conjugate (ADC) synthesis.

H2N-PEG8-tBu(756526-06-4)Related Product Information

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