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BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl-

Basic information Safety Supplier Related

BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl- Basic information

Product Name:
BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl-
Synonyms:
  • BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl-
  • 2-(3-iodo-1H-indazol-6-ylthio)-N-MethylbenzaMide
  • 2-[(3-Iodo-1H-indazol-6-yl)sulfanyl]-N-methylbenzamide
  • Axitinib Impurity f
  • Axitinib impurity H
  • Axitinib Impurity 2/2-[(3-iodo-2H-indazol-6-yl)sulfanyl]-N-methylbenzamide
  • 2-[(3-iodo-2H-indazol-6-yl)sulfanyl]-N-methylbenzamide
  • Axitinib Impurity O
CAS:
885126-34-1
MF:
C15H12IN3OS
MW:
409.24
Product Categories:
  • Intermediate
Mol File:
885126-34-1.mol
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BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl- Chemical Properties

Boiling point:
613.9±45.0 °C(Predicted)
Density 
1.80±0.1 g/cm3(Predicted)
pka
11.06±0.40(Predicted)
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Safety Information

HS Code 
2933998090
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BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl- Usage And Synthesis

Description

2-[(3-Iodo-1H-indazol-6-yl)sulfanyl]-N-methylbenzamide is a palladium catalyst for the synthesis of 2-[(3-iodo-1H-indazol-6-yl)sulfanyl]benzoic acid from 3,4 dinitrobenzoyl chloride and 1,2 dimethoxyethane. The reaction proceeds via a nucleophilic substitution reaction with the sulfonyl halide. The Iodo group can be replaced by other groups such as bromine, chlorine or fluorine in order to synthesize different derivatives of the compound.

Synthesis

Synthesis of 2-((3-Iodo-1H-indazol-6-yl)thio)-N-methylbenzamide from 3,6-Diiodo-1H-indazole and 2-Mercapto-N-methylbenzamide.

BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl-Supplier

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