BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl- Chemical Properties

Boiling point:

613.9±45.0 °C(Predicted)

Density 

1.80±0.1 g/cm3(Predicted)

pka

11.06±0.40(Predicted)

InChI

InChI=1S/C15H12IN3OS/c1-17-15(20)11-4-2-3-5-13(11)21-9-6-7-10-12(8-9)18-19-14(10)16/h2-8H,1H3,(H,17,20)(H,18,19)

InChIKey

VHZLHFNNNDGPLF-UHFFFAOYSA-N

SMILES

C(NC)(=O)C1=CC=CC=C1SC1=CC2=C(C=C1)C(I)=NN2

Safety Information

HS Code 

2933998090

BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl- Usage And Synthesis

Description

2-[(3-Iodo-1H-indazol-6-yl)sulfanyl]-N-methylbenzamide is a palladium catalyst for the synthesis of 2-[(3-iodo-1H-indazol-6-yl)sulfanyl]benzoic acid from 3,4 dinitrobenzoyl chloride and 1,2 dimethoxyethane. The reaction proceeds via a nucleophilic substitution reaction with the sulfonyl halide. The Iodo group can be replaced by other groups such as bromine, chlorine or fluorine in order to synthesize different derivatives of the compound.

Synthesis

Synthesis of 2-((3-Iodo-1H-indazol-6-yl)thio)-N-methylbenzamide from 3,6-Diiodo-1H-indazole and 2-Mercapto-N-methylbenzamide.

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