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MOTILIN (CANINE)

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MOTILIN (CANINE) Basic information

Product Name:
MOTILIN (CANINE)
Synonyms:
  • PHE-VAL-PRO-ILE-PHE-THR-HIS-SER-GLU-LEU-GLN-LYS-ILE-ARG-GLU-LYS-GLU-ARG-ASN-LYS-GLY-GLN
  • MOTILIN (CANINE)
  • FVPIFTHSELQKIREKERNKGQ
  • GASTRIC MOTOR STIMULATORY PEPTIDE, CANINE
  • H-PHE-VAL-PRO-ILE-PHE-THR-HIS-SER-GLU-LEU-GLN-LYS-ILE-ARG-GLU-LYS-GLU-ARG-ASN-LYS-GLY-GLN-OH
  • MOTILIN, CANINE ≥97%
  • CANINE MOTILINE)
  • Motilin (Canis familiaris)
CAS:
85490-53-5
MF:
C120H194N36O34
MW:
2685.09
Product Categories:
  • Peptide
  • Other Peptides
  • Peptides and Proteins
  • Peptides for Cell Biology
Mol File:
85490-53-5.mol
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MOTILIN (CANINE) Chemical Properties

Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
−20°C
form 
Solid
color 
White to off-white
Sequence
Phe-Val-Pro-Ile-Phe-Thr-His-Ser-Glu-Leu-Gln-Lys-Ile-Arg-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln
InChIKey
UXNMKJPZQNQTMI-IUYTUPPNNA-N
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Safety Information

WGK Germany 
3

MSDS

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MOTILIN (CANINE) Usage And Synthesis

Uses

Motilin, canine is a 22-amino acid peptide. Motilin is a potent agonist for gastrointestinal smooth muscle contraction.

in vivo

Motilin is a potent agonist for gastrointestinal smooth muscle contraction and has been proposed to regulate the onset of phase III of the migrating motor complex (MMC) in dogs and humans. In the dog, but not in the human, Motilin also contracts the gallbladder and sphincter of Oddi and induces pancreatic secretion. Motilin activates L-type Ca2+ channel (IcaL) in canine jejunal circular smooth muscle cells through a G protein-coupled mechanism. At 1 μM, Motilin increases IcaL in canine jejunal circular smooth muscle cells by 43±20[1].

References

[1] Farrugia G, et al. Motilin and OHM-11526 activate a calcium current in human and canine jejunal circular smooth muscle. Am J Physiol. 1997 Aug;273(2 Pt 1):G404-12. DOI:10.1152/ajpgi.1997.273.2.G404

MOTILIN (CANINE)Supplier

Phygene Gold
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18059081430
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2070812664@qq.com
GL Biochem (Shanghai) Ltd
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21-61263452 13641803416
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ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
Chemsky (shanghai) International Co.,Ltd
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021-50135380
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shchemsky@sina.com
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
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