(1S,2S,3S,4R)-Methyl 3-((R)-1-aMino-2-ethylbutyl)-4-(tert-butoxycarbonylaMino)-2-hydroxycyclopentanecarboxylate Chemical Properties

Boiling point:

476.5±45.0 °C(Predicted)

Density 

1.10±0.1 g/cm3(Predicted)

pka

11.63±0.70(Predicted)

InChI

InChI=1S/C18H34N2O5/c1-7-10(8-2)14(19)13-12(20-17(23)25-18(3,4)5)9-11(15(13)21)16(22)24-6/h10-15,21H,7-9,19H2,1-6H3,(H,20,23)/t11-,12+,13+,14-,15+/m0/s1

InChIKey

SECXLAHYOAZIGA-VYDRJRHOSA-N

SMILES

[C@H]1(C(OC)=O)C[C@@H](NC(OC(C)(C)C)=O)[C@H]([C@@H](N)C(CC)CC)[C@@H]1O

(1S,2S,3S,4R)-Methyl 3-((R)-1-aMino-2-ethylbutyl)-4-(tert-butoxycarbonylaMino)-2-hydroxycyclopentanecarboxylate Usage And Synthesis

Uses

(1S,2S,3S,4R)-3-[(1S)-1-Amino-2-ethylbutyl]-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxycyclopentanecarboxylic Acid Methyl Ester is an intermediate used in the synthesis of peramivir (P285500), a neuraminidase inhibitor developed as an antiviral agent for the treatment of influenza.

(1S,2S,3S,4R)-Methyl 3-((R)-1-aMino-2-ethylbutyl)-4-(tert-butoxycarbonylaMino)-2-hydroxycyclopentanecarboxylate(316173-29-2)Related Product Information

• Peramivir trihydrate
• Peramivir
• (1S,4R)-Methyl 4-aMinocyclopent-2-enecarboxylate hydrochloride
• (1R,4S)-Methyl 4-aMinocyclopent-2-enecarboxylate (Hydrochloride)
• Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester
• Peramivir Impurity 6
• 4-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-2-CYCLOPENTENE-1-CARBOXYLIC ACID METHYL ESTER
• (1S,2S,3R,4R)-Methyl 3-((R)-1-acetaMido-2-ethylbutyl)-4-aMino-2-hydroxycyclopentanecarboxylate
• Peramivir Impurity 75
• Peramivir Impurity 70
• Peramivir Impurity 58
• Peramivir Impurity 36
• Peramivir Impurity 31
• Peramivir Impurity 20
• Peramivir Impurity 16
• Peramivir Impurity 9
• Peramivir Impurity 4
• Peramivir Impurity 78