(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate Chemical Properties

Density 

1.5g/cm3 at 20℃

vapor pressure 

0-0Pa at 20-25℃

storage temp. 

Inert atmosphere,Room Temperature

form 

Solid

Appearance

White to off-white Solid

InChI

InChI=1/C6H10N2O.CH4O3S/c7-6(9)5-2-3-1-4(3)8-5;1-5(2,3)4/h3-5,8H,1-2H2,(H2,7,9);1H3,(H,2,3,4)/t3-,4-,5-;/s3

InChIKey

WPIYZQBALIBMAA-JBDXKQRLNA-N

SMILES

S(O)(=O)(=O)C.C([C@H]1N[C@H]2C[C@H]2C1)(=O)N |&1:6,8,10,r|

LogP

-2.9--1.1 at 20℃ and pH7

Surface tension

74.4mN/m at 1g/L and 20℃

(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate Usage And Synthesis

Uses

(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate is a pharmaceutical intermediate compound used in the preparation of saxagliptin and its hydrochloride salt. saxagliptin is a DPP-4 inhibitor used in the treatment of type 2 diabetes mellitus.

(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate(709031-45-8)Related Product Information

• Saxagliptin hydrate
• (1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide hydrochloride
• (S) - N- Boc- adamantylglycine