4-O-Methylsappanol
4-O-Methylsappanol Basic information
- Product Name:
- 4-O-Methylsappanol
- Synonyms:
-
- 4-O-Methylsappanol
- 2H-1-Benzopyran-3,7-diol, 3-[(3,4-dihydroxyphenyl)methyl]-3,4-dihydro-4-methoxy-, (3R,4S)-
- (3R,4S)-3-(3,4-Dihydroxybenzyl)-4-methoxy-3,7-chromanediol
- (3R,4S)-3-[(3,4-dihydroxyphenyl)methyl]-4-methoxy-2,4-dihydrochromene-3,7-diol
- CAS:
- 104778-16-7
- MF:
- C17H18O6
- MW:
- 318.32
- Mol File:
- 104778-16-7.mol
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4-O-Methylsappanol Chemical Properties
- Melting point:
- 156-158 °C
- Boiling point:
- 564.0±50.0 °C(Predicted)
- Density
- 1.48±0.1 g/cm3(Predicted)
- pka
- 9.68±0.60(Predicted)
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4-O-Methylsappanol Usage And Synthesis
Uses
4-O-Methylsappanol is a natural isoflavonoid with antifungal activities. 4-O-Methylsappanol shows activity against Beauveria bassiana[1]. 4-O-Methylsappanol (EC50 of 4.6 μM) strongly suppresses Melanin (Melanin) synthesis in HMV-II cells[2].
References
[1] V L Niranjan Reddy, et al. Inhibitory activity of homoisoflavonoids from Caesalpinia sappan against Beauveria bassiana. Fitoterapia. 2003 Sep;74(6):600-2. DOI:10.1016/s0367-326x(03)00153-9
[2] Kaoru Mitani, et al. Suppression of melanin synthesis by the phenolic constituents of sappanwood (Caesalpinia sappan). Planta Med. 2013 Jan;79(1):37-44. DOI:10.1055/s-0032-1327897
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