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Lethedioside A

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Lethedioside A Basic information

Product Name:
Lethedioside A
Synonyms:
  • Lethedioside A
  • 2-(3,4-Dimethoxyphenyl)-7-methoxy-5-[(6-O-beta-D-xylopyranosyl-beta-D-glucopyranosyl)oxy]-4H-1-benzopyran-4-one
  • 2-(3,4-Dimethoxyphenyl)-7-methoxy-4-oxo-4H-chromen-5-yl 6-O-β-D-xylopyranosyl-β-D-glucopyranoside
  • 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-7-methoxy-5-[(6-O-β-D-xylopyranosyl-β-D-glucopyranosyl)oxy]-
CAS:
221289-31-2
MF:
C29H34O15
MW:
622.57126
Mol File:
221289-31-2.mol
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Lethedioside A Chemical Properties

solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
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Lethedioside A Usage And Synthesis

Description

Lethedoside A was either inactive or weakly active against KB tumor cells, in contrast to previously isolated flavones from the same plant.

Uses

Lethedioside A is an Enhancer of split 1 (Hes1) dimer inhibitor with an IC50 value of 9.5 μM[1].

References

[1] Midori A Arai, et al. Hes1 inhibitor isolated by target protein oriented natural products isolation (TPO-NAPI) of differentiation activators of neural stem cells. Chem Sci. 2016 Feb 1;7(2):1514-1520. DOI:10.1039/c5sc03540f

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