Basic information Safety Supplier Related

2-(tert-ButylaMino)-3',5'-chloropropiophenone hydrochloride

Basic information Safety Supplier Related

2-(tert-ButylaMino)-3',5'-chloropropiophenone hydrochloride Basic information

Product Name:
2-(tert-ButylaMino)-3',5'-chloropropiophenone hydrochloride
Synonyms:
  • Bupropion 3',5'-Dichloro IMpurity
  • 2-(tert-Butylamino)-3',5'-chloropropiophenone
  • 2-(tert-butylamino)-3',5'-dichloropropiophenone
  • Bupropion Impurity 11(3,5-Chloro)
  • 1-Propanone, 1-(3,5-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-
  • 1-(3,5-Dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone
  • 5-chloro bupropion impurity
  • 3,5-Dichloro Bupropion
CAS:
1193779-48-4
MF:
C13H17Cl2NO
MW:
274.19
Mol File:
1193779-48-4.mol
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2-(tert-ButylaMino)-3',5'-chloropropiophenone hydrochloride Chemical Properties

Boiling point:
368.4±42.0 °C(Predicted)
Density 
1.158±0.06 g/cm3(Predicted)
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
6.92±0.39(Predicted)
form 
Solid
color 
Light Yellow
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2-(tert-ButylaMino)-3',5'-chloropropiophenone hydrochloride Usage And Synthesis

Uses

1-(3,5-Dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone is an intermediate in the synthesis of 5-Chloro Bupropion Fumarate (C364765). A 5-chloro substitued analogue of Bupropion (B689625) used in the preparation of compounds for indirect dopamine agonist pharmacotherapy for treating cocaine, methamphetamine, nicotine, and other drugs of abuse addiction.

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