3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one Chemical Properties

Melting point:

145-148°C

Boiling point:

437.4±55.0 °C(Predicted)

Density 

1.38±0.1 g/cm3(Predicted)

vapor pressure 

0-0Pa at 20-25℃

storage temp. 

-20°C Freezer

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

8.09±0.20(Predicted)

form 

Solid

color 

Beige

LogP

0.19 at 20℃ and pH7

3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one Usage And Synthesis

Uses

9-Hydroxy-3-(2-hydroxyethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is an intermediate in the synthesis of analog of Paliperidone, a combined serotonin and dopamine receptor antagonist.

3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one(181525-38-2)Related Product Information

• 9-Keto Risperidone
• 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
• 3-Ethyl-6,7,8,9-tetrahydro-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one
• Paliperidone N-Oxide
• 9-hydroxy-2-methyl-3-vinyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
• Paliperidone
• (R)-9-Hydroxy Risperidone
• 5-Fluoro Paliperidone
• 9-Benxyloxy-3-(2-Chloro ethyl)-2-methyl pyrido[1,2-a]pyrimidine-4-one
• (S)-9-Hydroxy Risperidone
• 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride
• 3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone)
• 3-ethyl-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one
• Paliperidone Desfluoro Impurity
• 9-(benzyloxy)-3-(2-hydroxyethyl)-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one