DIPROTIN A Chemical Properties

Boiling point:

583.1±50.0 °C(Predicted)

Density 

1.140±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

DMSO:250.0(Max Conc. mg/mL);732.17(Max Conc. mM)
Water:67.08(Max Conc. mg/mL);196.44(Max Conc. mM)

pka

3.72±0.22(Predicted)

form 

White to off-white solid.

color 

White to off-white

Water Solubility 

Soluble in water at 1mg/ml

CAS DataBase Reference

90614-48-5(CAS DataBase Reference)

Safety Information

WGK Germany 

3

RTECS 

NR4737000

MSDS

• Language:English Provider:SigmaAldrich

DIPROTIN A Usage And Synthesis

Uses

Ile-Pro-Ile has been used as a supplement for blood collection for hormone measurement and used in Islets cell culture to stabilize glucagon-like peptide-1 (GLP-1). It has also been used to inhibit the breakdown of gonadotropin-inhibitory hormone (GnIH) following serum collection.

Uses

As New dipeptidyl peptidase IV inhibitors (Diprotin A) and their uses as anti-cancer agents

Definition

ChEBI: (2S,3S)-2-[[[(2S)-1-[(2S,3S)-2-amino-3-methyl-1-oxopentyl]-2-pyrrolidinyl]-oxomethyl]amino]-3-methylpentanoic acid is a peptide.

Biochem/physiol Actions

Inhibitor of dipeptidyl peptidase IV. Inhibits entry of HIV-1 or HIV-2 into T lymphoblastoid and monocytoid cell lines.

storage

Store at -20°C

DIPROTIN A(90614-48-5)Related Product Information

• DIPROTIN B
• 1-Butylpyrrolidine
• 1-(2-Aminoethyl)pyrrolidine
• 2-(Aminomethyl)-1-ethylpyrrolidine
• DL-Isoleucine
• DIPROTIN A
• DIPEPTIDYLPEPTIDASE IV
• GLYCINE-NME2 ACETATE
• (1-ETHYLPYRROLIDIN-2-YL)-N-METHYLMETHANAMINE
• (S)-2-AMINO-3-METHYL-1-(PYRROLIDIN-1-YL)BUTAN-1-ONE
• CNTSVITQACPKISFEPIPI
• H-PRO-VAL-OH
• H-ALA-PRO-GLY-OH
• H-PRO-ALA-OH
• H-GLY-PRO-GLY-OH
• H-GLY-PRO-ALA-OH
• H-ALA-PRO-ALA-OH
• H-PRO-ILE-OH