Basic information Safety Supplier Related

DIPROTIN A

Basic information Safety Supplier Related

DIPROTIN A Basic information

Product Name:
DIPROTIN A
Synonyms:
  • n-(1-l-isoleucyl-l-prolyl)-l-isoleucin
  • n-(1-l-isoleucyl-l-prolyl)-l-isoleucine
  • DIPROTIN A
  • DIPROTIN A H2O
  • DIPEPTIDYLPEPTIDASE IV INHIBITOR I
  • ILE-PRO-ILE
  • ILE-PRO-ILE H2O
  • H-ILE-PRO-ILE-OH
CAS:
90614-48-5
MF:
C17H31N3O4
MW:
341.45
Product Categories:
  • Chiral Reagents
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Pepetides
  • peptides
Mol File:
90614-48-5.mol
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DIPROTIN A Chemical Properties

Boiling point:
583.1±50.0 °C(Predicted)
Density 
1.140±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO:250.0(Max Conc. mg/mL);732.17(Max Conc. mM)
Water:67.08(Max Conc. mg/mL);196.44(Max Conc. mM)
pka
3.72±0.22(Predicted)
form 
White to off-white solid.
Water Solubility 
Soluble in water at 1mg/ml
CAS DataBase Reference
90614-48-5(CAS DataBase Reference)
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Safety Information

WGK Germany 
3
RTECS 
NR4737000

MSDS

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DIPROTIN A Usage And Synthesis

Uses

Ile-Pro-Ile has been used as a supplement for blood collection for hormone measurement and used in Islets cell culture to stabilize glucagon-like peptide-1 (GLP-1). It has also been used to inhibit the breakdown of gonadotropin-inhibitory hormone (GnIH) following serum collection.

Uses

As New dipeptidyl peptidase IV inhibitors (Diprotin A) and their uses as anti-cancer agents

Definition

ChEBI: (2S,3S)-2-[[[(2S)-1-[(2S,3S)-2-amino-3-methyl-1-oxopentyl]-2-pyrrolidinyl]-oxomethyl]amino]-3-methylpentanoic acid is a peptide.

Biochem/physiol Actions

Inhibitor of dipeptidyl peptidase IV. Inhibits entry of HIV-1 or HIV-2 into T lymphoblastoid and monocytoid cell lines.

storage

Store at -20°C

DIPROTIN ASupplier

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