ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Other amino acid derivatives > L-2-Aminoadipic acid
L-2-Aminoadipic acid
L-2-Aminoadipic acid Basic information
- Product Name:
- L-2-Aminoadipic acid
- Synonyms:
-
- ALPHA-AMINOHEXANDIOIC ACID
- AMINOADIPIC ACID, L-2-
- AAD
- 2-AMINO-HEXANEDIOIC ACID
- H-L-HOGLU-OH
- HOMOGLUTAMIC ACID
- H-HOMOGLU-OH
- HEXANEDIOIC ACID, 2-AMINO-, (2S)-
- CAS:
- 1118-90-7
- MF:
- C6H11NO4
- MW:
- 161.16
- EINECS:
- 601-134-8
- Product Categories:
-
- Amino Acids
- Biochemistry
- non-Proteinorganic Amino Acids
- Mol File:
- 1118-90-7.mol
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L-2-Aminoadipic acid Chemical Properties
- Melting point:
- 203-205 °C (dec.)(lit.)
- alpha
- 22 º (c=2, 5 N HCl 25 ºC)
- Boiling point:
- 287.44°C (rough estimate)
- Density
- 1.3482 (rough estimate)
- refractive index
- 1.4230 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- 1N HCl: 10 mg/ml; PBS (pH 7.2): 0.5 mg/ml
- form
- Solid
- pka
- 2.49±0.24(Predicted)
- color
- White
- Water Solubility
- Soluble in 1N HCl (50 mg/ml) and water (slightly).
- BRN
- 1724348
- InChIKey
- OYIFNHCXNCRBQI-BYPYZUCNSA-N
- CAS DataBase Reference
- 1118-90-7(CAS DataBase Reference)
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 29224999
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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L-2-Aminoadipic acid Usage And Synthesis
Chemical Properties
WHITE SOLID
Uses
An inhibitor of ischemic glutamate release
Uses
L-2-Aminoadipic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
Definition
ChEBI: The L-enantiomer of 2-aminoadipic acid.
General Description
L-2-Aminoadipic acid/α-aminoadipate is a gliotoxin and is a structural analog of glutamine. It is generated by the catabolism of lysine saccharopine (SAC)/pipecolic acid (PIP) pathways.
Biochem/physiol Actions
L-2-Aminoadipic acid inhibits glutamine synthetase and γ-glutamylcysteine synthetase. It modulates glucose metabolism and is present in higher levels in diabetic patients. L-2-Aminoadipic acid plays a key role in suppressing autophagy in C2C12 myotubes.
L-2-Aminoadipic acidSupplier
Nanjing Derno Pharmaceutical Technology Co., Ltd. Gold
- Tel
- 025-86957866 13952093866
- sales@dernopharm.com
Jinan Kabotang Biological Technology Co.,Ltd. Gold
- Tel
- 0531-61320525 15866703830
- 495745175@qq.com
Shanxi Bethlehem Pharm-Tech Co.,Ltd. Gold
- Tel
- 19135651206 19135651206
- 243332738@qq.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
PharmaBlock Sciences (Nanjing),Inc.
- Tel
- 025-86918202 4000255188
- sales@pharmablock.com
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L-2-Aminoadipic acid(1118-90-7)Related Product Information
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- Stearic acid
- Adipic dihydrazide
- Citric acid
- Dimethyl adipate
- Adipic acid
- Folic acid
- Bis(2-ethylhexyl) adipate
- Ammonium adipate
- Hyaluronic acid
- POLY(1 6-HEXAMETHYLENE ADIPATE) AVERAG&
- Ascoric Acid
- NALPHA-tert-Butoxycarbonyl-L-2-aminoadipic acid,Boc-L-homoglutamic acid, N-Boc-L-2-aminoadipic acid,BOC-L-2-AMINOADIPIC ACID,BOC-L-ALPHA-AMINOADIPIC ACID
- FMOC-L-ALPHA-AMINOADIPIC ACID-DELTA-T-BUTYL ESTER
- (2S,1'S,2'S)-2-(CARBOXYCYCLOPROPYL)GLYCINE
- D-2-Aminoadipic acid,(R)-2-Aminoadipic acid,[R,(-)]-2-Aminoadipic acid
- (S)-3-Aminoadipic acid hydrochloride, (S)-3-Aminohexanedioic acid hydrochloride
- 3-AMINOADIPIC ACID