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(R)-N-FMoc-2-(2'-propynyl)alanine

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(R)-N-FMoc-2-(2'-propynyl)alanine Basic information

Product Name:
(R)-N-FMoc-2-(2'-propynyl)alanine
Synonyms:
  • (R)-N-FMoc-2-(2'-propynyl)alanine
  • (R)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-2-Methylpent-4-ynoic acid
  • (R)-N-FMOC-Α-PROPARGYLALANINE
  • FMoc-α-Me-D-Gly(Propargyl)-OH
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-D-Gly(Propargyl)-OH
  • Fmoc-alpha-Prg-L-Ala-OH
  • (R)-N-Fmoc-2-(2'-propynyl)alanine, >97%
  • (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpent-4-ynoic acid
CAS:
1198791-65-9
MF:
C21H19NO4
MW:
349.38
Product Categories:
  • α-Methyl Amino Acids
Mol File:
1198791-65-9.mol
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(R)-N-FMoc-2-(2'-propynyl)alanine Chemical Properties

Boiling point:
576.8±50.0 °C(Predicted)
Density 
1.267±0.06 g/cm3(Predicted)
storage temp. 
-20°C
pka
3.51±0.11(Predicted)
form 
liquid
color 
pale yellow
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Safety Information

Hazard Codes 
Xn
Risk Statements 
36-42/43
Safety Statements 
22-26-36/37-45
TSCA 
No
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(R)-N-FMoc-2-(2'-propynyl)alanine Usage And Synthesis

Uses

Fmoc-?(R)?-?propargyl-?Ala-?OH is a chiral reagent used in the preparation of peptidomimetic macrocycles for the transport of biomolecules.

Uses

Alkyne amino acid, more stable for peptide stapling via click chemistry than propargylglycine.

reaction suitability

reaction type: click chemistry

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